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bpp: Computations Around Bayesian Predictive Power

Implements functions to update Bayesian Predictive Power Computations after not stopping a clinical trial at an interim analysis. Such an interim analysis can either be blinded or unblinded. Code is provided for Normally distributed endpoints with known variance, with a prominent example being the hazard ratio.

Version: 1.0.4
Depends: mvtnorm, R (≥ 2.10)
Suggests: knitr, rmarkdown
Published: 2022-01-13
DOI: 10.32614/CRAN.package.bpp
Author: Kaspar Rufibach, Paul Jordan, Markus Abt
Maintainer: Kaspar Rufibach <kaspar.rufibach at roche.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
Materials: NEWS
CRAN checks: bpp results

Documentation:

Reference manual: bpp.pdf
Vignettes: Sequentially updating the likelihood of success of a Phase 3 pivotal time-to-event trial based on interim analyses or external information

Downloads:

Package source: bpp_1.0.4.tar.gz
Windows binaries: r-devel: bpp_1.0.4.zip, r-release: bpp_1.0.4.zip, r-oldrel: bpp_1.0.4.zip
macOS binaries: r-release (arm64): bpp_1.0.4.tgz, r-oldrel (arm64): bpp_1.0.4.tgz, r-release (x86_64): bpp_1.0.4.tgz, r-oldrel (x86_64): bpp_1.0.4.tgz
Old sources: bpp archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=bpp to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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