The hardware and bandwidth for this mirror is donated by dogado GmbH, the Webhosting and Full Service-Cloud Provider. Check out our Wordpress Tutorial.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]dogado.de.
The R package 'ashr' implements an Empirical Bayes approach for large-scale hypothesis testing and false discovery rate (FDR) estimation based on the methods proposed in M. Stephens, 2016, "False discovery rates: a new deal", <doi:10.1093/biostatistics/kxw041>. These methods can be applied whenever two sets of summary statistics—estimated effects and standard errors—are available, just as 'qvalue' can be applied to previously computed p-values. Two main interfaces are provided: ash(), which is more user-friendly; and ash.workhorse(), which has more options and is geared toward advanced users. The ash() and ash.workhorse() also provides a flexible modeling interface that can accommodate a variety of likelihoods (e.g., normal, Poisson) and mixture priors (e.g., uniform, normal).
Version: | 2.2-63 |
Depends: | R (≥ 3.1.0) |
Imports: | Matrix, stats, graphics, Rcpp (≥ 0.10.5), truncnorm, mixsqp, SQUAREM, etrunct, invgamma |
LinkingTo: | Rcpp |
Suggests: | testthat, knitr, rmarkdown, ggplot2, REBayes |
Published: | 2023-08-21 |
DOI: | 10.32614/CRAN.package.ashr |
Author: | Matthew Stephens [aut], Peter Carbonetto [aut, cre], Chaoxing Dai [ctb], David Gerard [aut], Mengyin Lu [aut], Lei Sun [aut], Jason Willwerscheid [aut], Nan Xiao [aut], Mazon Zeng [ctb] |
Maintainer: | Peter Carbonetto <pcarbo at uchicago.edu> |
BugReports: | https://github.com/stephens999/ashr/issues |
License: | GPL (≥ 3) |
URL: | https://github.com/stephens999/ashr |
NeedsCompilation: | yes |
Materials: | NEWS |
In views: | Bayesian |
CRAN checks: | ashr results |
Reference manual: | ashr.pdf |
Vignettes: |
Illustration of Adaptive Shrinkage |
Package source: | ashr_2.2-63.tar.gz |
Windows binaries: | r-devel: ashr_2.2-63.zip, r-release: ashr_2.2-63.zip, r-oldrel: ashr_2.2-63.zip |
macOS binaries: | r-release (arm64): ashr_2.2-63.tgz, r-oldrel (arm64): ashr_2.2-63.tgz, r-release (x86_64): ashr_2.2-63.tgz, r-oldrel (x86_64): ashr_2.2-63.tgz |
Old sources: | ashr archive |
Reverse depends: | mashr |
Reverse imports: | cytoKernel, debrowser, DiffBind, dreamlet, ebnm, fastTopics, ldsep, limorhyde2, MixTwice, QTLExperiment |
Reverse suggests: | BindingSiteFinder, dar, DESeq2, flashier, ncvreg, ribosomeProfilingQC, topconfects |
Reverse enhances: | palasso |
Please use the canonical form https://CRAN.R-project.org/package=ashr to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.