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Automated methods to assemble population PK (pharmacokinetic) and PKPD (pharmacodynamic) datasets for analysis in 'NONMEM' (non-linear mixed effects modeling) by Bauer (2019) <doi:10.1002/psp4.12404>. The package includes functions to build datasets from SDTM (study data tabulation module) <https://www.cdisc.org/standards/foundational/sdtm>, ADaM (analysis dataset module) <https://www.cdisc.org/standards/foundational/adam>, or other dataset formats. The package will combine population datasets, add covariates, and create documentation to support regulatory submission and internal communication.
| Version: | 1.1.1 |
| Depends: | R (≥ 4.00) |
| Imports: | dplyr, tidyr, purrr, this.path, flextable, officer, tidyselect, utils, arsenal |
| Suggests: | rmarkdown, knitr, testthat, tibble |
| Published: | 2024-01-09 |
| DOI: | 10.32614/CRAN.package.apmx |
| Author: | Stephen Amori [aut, cre, cph], Ethan DellaMaestra [aut], Michael Dick [aut], Daniel Litow [ctb], Jonah Lyon [ctb] |
| Maintainer: | Stephen Amori <stephen.amori at amadorbio.com> |
| BugReports: | https://github.com/stephen-amori/apmx/issues |
| License: | GPL (≥ 3) |
| URL: | https://github.com/stephen-amori/apmx |
| NeedsCompilation: | no |
| Materials: | README NEWS |
| CRAN checks: | apmx results |
| Reference manual: | apmx.pdf |
| Vignettes: |
PKPD_analysis |
| Package source: | apmx_1.1.1.tar.gz |
| Windows binaries: | r-devel: apmx_1.1.1.zip, r-release: apmx_1.1.1.zip, r-oldrel: apmx_1.1.1.zip |
| macOS binaries: | r-release (arm64): apmx_1.1.1.tgz, r-oldrel (arm64): apmx_1.1.1.tgz, r-release (x86_64): apmx_1.1.1.tgz, r-oldrel (x86_64): apmx_1.1.1.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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