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amp.sim: Flexible Simulation Utilities for Pharmacometric Modeling

The goal of 'amp.sim' is to transform 'NONMEM' models into R syntax so they can be used for simulations using the 'deSolve', 'nlmixr2' or 'mrgsolve' package. Additionally, functionality is included to aid simulations performed directly in 'NONMEM' and to automatically create shiny apps for simulation models.

Version: 0.1.0
Depends: R (≥ 4.1.0)
Imports: stats, utils, MASS, whisker, rlang, cli, lifecycle, NMdata (≥ 0.2.3)
Suggests: nonmem2rx, tidyr, shiny, shinyjs, bslib, rstudioapi, deSolve, rxode2, mrgsolve, R3port, ggplot2, dplyr, testthat, quarto
Published: 2026-05-07
DOI: 10.32614/CRAN.package.amp.sim (may not be active yet)
Author: Richard Hooijmaijers [aut, cre, cph], LAPP Consultants [fnd, cph]
Maintainer: Richard Hooijmaijers <richardhooijmaijers at gmail.com>
BugReports: https://github.com/LeidenAdvancedPKPD/amp.sim/issues
License: GPL (≥ 3)
URL: https://leidenadvancedpkpd.github.io/amp.sim/, https://github.com/LeidenAdvancedPKPD/amp.sim
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: amp.sim results

Documentation:

Reference manual: amp.sim.html , amp.sim.pdf
Vignettes: Simulations using R (source, R code)
Simulations using NONMEM (source, R code)
Shiny apps (source, R code)
Considerations for translating models (source, R code)

Downloads:

Package source: amp.sim_0.1.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): amp.sim_0.1.0.tgz, r-oldrel (arm64): amp.sim_0.1.0.tgz, r-release (x86_64): amp.sim_0.1.0.tgz, r-oldrel (x86_64): amp.sim_0.1.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=amp.sim to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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