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Implementation of a model-based bootstrap approach for testing whether two formulations are similar. The package provides a function for fitting a pharmacokinetic model to time-concentration data and comparing the results for all five candidate models regarding the Residual Sum of Squares (RSS). The candidate set contains a First order, Hixson-Crowell, Higuchi, Weibull and a logistic model. The assessment of similarity implemented in this package is performed regarding the maximum deviation of the profiles. See Moellenhoff et al. (2018) <doi:10.1002/sim.7689> for details.
| Version: | 0.1.0 |
| Depends: | dplyr, alabama, mvtnorm, graphics |
| Published: | 2019-09-27 |
| DOI: | 10.32614/CRAN.package.SimDissolution |
| Author: | Kathrin Moellenhoff |
| Maintainer: | Kathrin Moellenhoff <kathrin.moellenhoff at rub.de> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | SimDissolution results |
| Reference manual: | SimDissolution.pdf |
| Package source: | SimDissolution_0.1.0.tar.gz |
| Windows binaries: | r-devel: SimDissolution_0.1.0.zip, r-release: SimDissolution_0.1.0.zip, r-oldrel: SimDissolution_0.1.0.zip |
| macOS binaries: | r-release (arm64): SimDissolution_0.1.0.tgz, r-oldrel (arm64): SimDissolution_0.1.0.tgz, r-release (x86_64): SimDissolution_0.1.0.tgz, r-oldrel (x86_64): SimDissolution_0.1.0.tgz |
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