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SelfControlledCaseSeries: Self-Controlled Case Series

Execute the self-controlled case series (SCCS) design using observational data in the OMOP Common Data Model. Extracts all necessary data from the database and transforms it to the format required for SCCS. Age and season can be modeled using splines assuming constant hazard within calendar months. Event-dependent censoring of the observation period can be corrected for. Many exposures can be included at once (MSCCS), with regularization on all coefficients except for the exposure of interest. Includes diagnostics for all major assumptions of the SCCS.

Version: 6.0.0
Depends: R (≥ 4.1.0), Cyclops (≥ 3.4.0), DatabaseConnector (≥ 6.0.0), Andromeda (≥ 1.0.0)
Imports: SqlRender (≥ 1.16.0), dplyr (≥ 1.0.0), Rcpp (≥ 1.0.9), ParallelLogger (≥ 3.4.0), EmpiricalCalibration, splines, ggplot2 (≥ 3.4.0), methods, utils, checkmate, readr, ResultModelManager, jsonlite, digest, R6
LinkingTo: Rcpp
Suggests: zip, testthat, knitr, rmarkdown, Eunomia, withr
Published: 2025-06-23
DOI: 10.32614/CRAN.package.SelfControlledCaseSeries
Author: Martijn Schuemie [aut, cre], Patrick Ryan [aut], Trevor Shaddox [aut], Marc Suchard [aut]
Maintainer: Martijn Schuemie <schuemie at ohdsi.org>
BugReports: https://github.com/OHDSI/SelfControlledCaseSeries/issues
License: Apache License 2.0
URL: https://ohdsi.github.io/SelfControlledCaseSeries/, https://github.com/OHDSI/SelfControlledCaseSeries
NeedsCompilation: yes
Materials: README NEWS
CRAN checks: SelfControlledCaseSeries results

Documentation:

Reference manual: SelfControlledCaseSeries.pdf
Vignettes: Multiple analyses using SelfControlledCaseSeries (source, R code)
Results schema (source, R code)
Single studies using SelfControlledCaseSeries (source, R code)

Downloads:

Package source: SelfControlledCaseSeries_6.0.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): SelfControlledCaseSeries_6.0.0.tgz, r-oldrel (arm64): SelfControlledCaseSeries_6.0.0.tgz, r-release (x86_64): SelfControlledCaseSeries_6.0.0.tgz, r-oldrel (x86_64): SelfControlledCaseSeries_6.0.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=SelfControlledCaseSeries to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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