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SPACO: Spatial Component Analysis for Spatial Sequencing Data

Spatial components offer tools for dimension reduction and spatially variable gene detection for high dimensional spatial transcriptomics data. Construction of a projection onto low-dimensional feature space of spatially dependent metagenes offers pre-processing to clustering, testing for spatial variability and denoising of spatial expression patterns. For more details, see Koehler et al. (2026) <doi:10.1093/bioinformatics/btag052>.

Version: 1.0.1
Depends: R (≥ 4.2.3)
Imports: ggplot2, Seurat (≥ 5.3.0), tibble, ggforce, methods, rARPACK, tidyr, mgcv, scales, Matrix (≥ 1.5)
LinkingTo: Rcpp, RcppEigen
Suggests: testthat (≥ 3.0.0)
Published: 2026-03-31
DOI: 10.32614/CRAN.package.SPACO
Author: David Köhler ORCID iD [aut, cre]
Maintainer: David Köhler <koehler at imbie.uni-bonn.de>
License: MIT + file LICENSE
NeedsCompilation: yes
CRAN checks: SPACO results

Documentation:

Reference manual: SPACO.html , SPACO.pdf

Downloads:

Package source: SPACO_1.0.1.tar.gz
Windows binaries: r-devel: SPACO_1.0.1.zip, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): SPACO_1.0.1.tgz, r-oldrel (arm64): not available, r-release (x86_64): SPACO_1.0.1.tgz, r-oldrel (x86_64): SPACO_1.0.1.tgz
Old sources: SPACO archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=SPACO to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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