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RZooRoH 0.4.2

• Improved memory usage - in particular for parallel computing
• More efficient computation of allele frequencies (C functions)
• Improved management of convergence problems:
  • possibility to automatically restart analysis in case of convergence problems by providing multiple optim methods or starting values for mixing coefficients,
  • improved error message, information on problematic individuals (or pairs),
  • added @optimerr slot to kinship results
• Improved numerical properties for ‘Interval’ models (better stability with very low values)
• New modelling of the minimum rate in MixKL models (compatible with more optim methods)
• New options to provide map directly in cM or in physical position but with a cM-to-Mb ratio different from 1
• Added new accessor functions for kinship results (update and merge), extended update and merge functions to IBD analyses
• Added new accessor function to estimate inbreeding coefficients based on identified HBD segments
• Corrections of minor bugs
• Updated documentation according to changes and clarified links between mixing coefficients and inbreeding rates per layer, and between “rates” and rates of coancestry changes
• Updated documentation on conversions (using PLINK2 and dosage formats)
• Modifications to the vignette, including advice for memory management and handling convergence problems
• Set freqem to TRUE by default
• Updated citations

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.