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Implements covariate-adjusted estimation and inference for marginal mean differences in two-arm randomized controlled trials with continuous outcomes. Methods include the unadjusted difference in means, common-slope analysis of covariance, interacted standardization with joint influence-function inference, and cross-fitted augmentation. The package also provides analytic power and sample-size calculations, reproducible simulation designs, and article replication workflows, including tools for verifying and analyzing an authorized local trial-data file. The adjustment methods build on Tsiatis et al. (2008) <doi:10.1002/sim.3113> and Lin (2013) <doi:10.1214/12-AOAS583>.
| Version: | 0.1.0 |
| Depends: | R (≥ 4.1.0) |
| Imports: | digest, graphics, grDevices, parallel, stats, tools, utils |
| Suggests: | knitr, medicaldata (≥ 0.2.0), rmarkdown, testthat (≥ 3.0.0), withr |
| Published: | 2026-09-24 |
| DOI: | 10.32614/CRAN.package.RCTCovAdj (may not be active yet) |
| Author: | Se Yoon Lee [aut, cre, cph] |
| Maintainer: | Se Yoon Lee <seyoonlee.stat.math at gmail.com> |
| License: | MIT + file LICENSE |
| NeedsCompilation: | no |
| Citation: | RCTCovAdj citation info |
| Materials: | README, NEWS |
| CRAN checks: | RCTCovAdj results |
| Reference manual: | RCTCovAdj.html , RCTCovAdj.pdf |
| Vignettes: |
Covariate Adjustment in Randomized Controlled Trials (source, R code) Reproducing the Paper's Numerical Results (source, R code) |
| Package source: | RCTCovAdj_0.1.0.tar.gz |
| Windows binaries: | r-devel: not available, r-release: RCTCovAdj_0.1.0.zip, r-oldrel: RCTCovAdj_0.1.0.zip |
| macOS binaries: | r-release (arm64): RCTCovAdj_0.1.0.tgz, r-oldrel (arm64): RCTCovAdj_0.1.0.tgz, r-release (x86_64): RCTCovAdj_0.1.0.tgz, r-oldrel (x86_64): RCTCovAdj_0.1.0.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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