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RARtrials: Response-Adaptive Randomization in Clinical Trials

Some response-adaptive randomization methods commonly found in literature are included in this package. These methods include the randomized play-the-winner rule for binary endpoint (Wei and Durham (1978) <doi:10.2307/2286290>), the doubly adaptive biased coin design with minimal variance strategy for binary endpoint (Atkinson and Biswas (2013) <doi:10.1201/b16101>, Rosenberger and Lachin (2015) <doi:10.1002/9781118742112>) and maximal power strategy targeting Neyman allocation for binary endpoint (Tymofyeyev, Rosenberger, and Hu (2007) <doi:10.1198/016214506000000906>) and RSIHR allocation with each letter representing the first character of the names of the individuals who first proposed this rule (Youngsook and Hu (2010) <doi:10.1198/sbr.2009.0056>, Bello and Sabo (2016) <doi:10.1080/00949655.2015.1114116>), A-optimal Allocation for continuous endpoint (Sverdlov and Rosenberger (2013) <doi:10.1080/15598608.2013.783726>), Aa-optimal Allocation for continuous endpoint (Sverdlov and Rosenberger (2013) <doi:10.1080/15598608.2013.783726>), generalized RSIHR allocation for continuous endpoint (Atkinson and Biswas (2013) <doi:10.1201/b16101>), Bayesian response-adaptive randomization with a control group using the Thall \& Wathen method for binary and continuous endpoints (Thall and Wathen (2007) <doi:10.1016/j.ejca.2007.01.006>) and the forward-looking Gittins index rule for binary and continuous endpoints (Villar, Wason, and Bowden (2015) <doi:10.1111/biom.12337>, Williamson and Villar (2019) <doi:10.1111/biom.13119>).

Version: 0.0.1
Depends: R (≥ 4.3), stats, pins
Imports: Rdpack (≥ 0.7)
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2024-06-04
DOI: 10.32614/CRAN.package.RARtrials
Author: Chuyao Xu [aut, cre], Thomas Lumley [aut, ths], Alain Vandal [aut, ths], Sofia S. Villar [cph], Kyle J. Wathen [cph]
Maintainer: Chuyao Xu <cxu870 at aucklanduni.ac.nz>
License: GPL (≥ 3)
URL: https://github.com/yayayaoyaoyao/RARtrials
NeedsCompilation: no
Materials: README
CRAN checks: RARtrials results

Documentation:

Reference manual: RARtrials.pdf
Vignettes: Response-Adaptive randomization in Clinical Trials

Downloads:

Package source: RARtrials_0.0.1.tar.gz
Windows binaries: r-devel: RARtrials_0.0.1.zip, r-release: RARtrials_0.0.1.zip, r-oldrel: RARtrials_0.0.1.zip
macOS binaries: r-release (arm64): RARtrials_0.0.1.tgz, r-oldrel (arm64): RARtrials_0.0.1.tgz, r-release (x86_64): RARtrials_0.0.1.tgz, r-oldrel (x86_64): RARtrials_0.0.1.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=RARtrials to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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