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PopED

PopED computes optimal experimental designs for both population and individual studies based on nonlinear mixed-effect models. Often this is based on a computation of the Fisher Information Matrix (FIM).

Installation

You need to have R installed. Download the latest version of R from www.r-project.org. You can install the released version of PopED from CRAN with:

install.packages("PopED")

And the development version from GitHub with:

# install.packages("devtools")
devtools::install_github("andrewhooker/PopED")

Getting started

To get started you need to define

1. A model.
2. An initial design (and design space if you want to optimize).
3. The tasks to perform.

Learn more in this introduction to PopED

Contact

You are welcome to:

• submit suggestions and bug-reports at: https://github.com/andrewhooker/PopED/issues
• send a pull request on: https://github.com/andrewhooker/PopED
• compose a friendly e-mail to: andrew.hooker@farmaci.uu.se

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
Health stats visible at Monitor.