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Type: Package
Title: Analyzing the Heterogeneity of Single-Cell Populations
Version: 0.2.0
Description: A bioinformatics method developed for analyzing the heterogeneity of single-cell populations. Phitest provides an objective and automatic method to evaluate the performance of clustering and quality of cell clusters.
License: GPL-3
Encoding: UTF-8
RoxygenNote: 7.1.1
Imports: parallel, fitdistrplus
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2022-01-21 01:33:49 UTC; wei
Author: Wei Vivian Li ORCID iD [aut, cre]
Maintainer: Wei Vivian Li <vivian.li@rutgers.edu>
Repository: CRAN
Date/Publication: 2022-01-21 09:13:00 UTC

Appling the Phitest method to a count matrix

Description

Phitest for analyzing the heterogeneity of single-cell populations

Usage

phitest(object, label, ncores = 1, min.cell = 10)

Arguments

object

A matrix of single-cell UMI counts (rows for genes and columns for cells).

label

A character or numeric vector of cluster labels. Length should be the same as cell number and order should match the order in object.

ncores

Number of cores used for parallel computation.

min.cell

An integer specifying a threshold to filter genes. Genes expressed in fewer than min.cell cells are filtered out.

Value

A list of two elements: pval contains the P values, and par contains the estimated parameters.

Author(s)

Wei Vivian Li, vivian.li@rutgers.edu

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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