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A system for fast, accurate, and flexible whole genome bisulfite sequencing (WGBS) data analysis of two-condition comparisons. Principle Component BiSulfite, 'PCBS', assigns methylated loci eigenvector values from the treatment-delineating principal component in lieu of running millions of pairwise statistical tests, which dramatically increases analysis flexibility and reduces computational requirements. Methods: <https://katlande.github.io/PCBS/articles/Differential_Methylation.html>.
Version: | 0.1.0 |
Depends: | R (≥ 2.10) |
Imports: | ggplot2, tibble, ggrepel, dplyr, data.table |
Published: | 2024-04-23 |
DOI: | 10.32614/CRAN.package.PCBS |
Author: | Kathryn Lande [aut, cre, cph] |
Maintainer: | Kathryn Lande <kathryn.lande at mail.mcgill.ca> |
BugReports: | https://github.com/katlande/PCBS/issues |
License: | GPL-3 |
URL: | https://github.com/katlande/PCBS |
NeedsCompilation: | no |
CRAN checks: | PCBS results |
Reference manual: | PCBS.pdf |
Package source: | PCBS_0.1.0.tar.gz |
Windows binaries: | r-devel: PCBS_0.1.0.zip, r-release: PCBS_0.1.0.zip, r-oldrel: PCBS_0.1.0.zip |
macOS binaries: | r-release (arm64): PCBS_0.1.0.tgz, r-oldrel (arm64): PCBS_0.1.0.tgz, r-release (x86_64): PCBS_0.1.0.tgz, r-oldrel (x86_64): PCBS_0.1.0.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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