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NORMAgene: Data-Driven qRT-PCR Normalization Using NORMAgene

Enables correction for technical variance in raw quantitative reverse transcription polymerase chain reaction (qRT-PCR) data using the least squares-based NORMAgene data-driven normalization algorithm originally described by Heckmann et al. (2011) <doi:10.1186/1471-2105-12-250>. Performs normalization of raw crossing threshold values (CT) and also calculates relative variability metrics that can be used to assess the impact of normalization on variance.

Version: 0.1.1
Depends: R (≥ 3.5)
Suggests: testthat (≥ 3.0.0)
Published: 2026-02-28
DOI: 10.32614/CRAN.package.NORMAgene
Author: Grant C. O'Connell ORCID iD [aut, cre]
Maintainer: Grant C. O'Connell <goconnell.phd at gmail.com>
License: GPL-3
NeedsCompilation: no
Citation: NORMAgene citation info
CRAN checks: NORMAgene results

Documentation:

Reference manual: NORMAgene.html , NORMAgene.pdf

Downloads:

Package source: NORMAgene_0.1.1.tar.gz
Windows binaries: r-devel: NORMAgene_0.1.1.zip, r-release: NORMAgene_0.1.1.zip, r-oldrel: NORMAgene_0.1.1.zip
macOS binaries: r-release (arm64): NORMAgene_0.1.1.tgz, r-oldrel (arm64): NORMAgene_0.1.1.tgz, r-release (x86_64): NORMAgene_0.1.1.tgz, r-oldrel (x86_64): NORMAgene_0.1.1.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=NORMAgene to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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