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MRIreduce: ROI-Based Transformation of Neuroimages into High-Dimensional Data Frames

Converts NIfTI format T1/FL neuroimages into structured, high-dimensional 2D data frames with a focus on region of interest (ROI) based processing. The package incorporates the partition algorithm, which offers a flexible framework for agglomerative partitioning based on the Direct-Measure-Reduce approach. This method ensures that each reduced variable maintains a user-specified minimum level of information while remaining interpretable, as each maps uniquely to one variable in the reduced dataset. The partition framework is described in Millstein et al. (2020) <doi:10.1093/bioinformatics/btz661>. The package allows customization in variable selection, measurement of information loss, and data reduction methods for neuroimaging analysis and machine learning workflows.

Version: 1.0.0
Depends: R (≥ 3.5.0)
Imports: R6, Rcpp, fslr, neurobase, oro.nifti, parallel, partition, reshape2, reticulate
LinkingTo: Rcpp
Suggests: DT, EveTemplate, knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2026-04-21
DOI: 10.32614/CRAN.package.MRIreduce
Author: Joshua Milstein [aut], Jinyao Tian [aut, cre]
Maintainer: Jinyao Tian <jinyaoti at usc.edu>
License: MIT + file LICENSE
URL: https://uscbiostats.github.io/MRIreduce/
NeedsCompilation: yes
SystemRequirements: FSL (FMRIB Software Library, available at https://fsl.fmrib.ox.ac.uk/fsl/docs/#/install/index)
Additional_repositories: https://neuroconductor.org/releases/2020/05
Language: en-US
Materials: README
CRAN checks: MRIreduce results

Documentation:

Reference manual: MRIreduce.html , MRIreduce.pdf
Vignettes: Introduction to MRIreduce (source, R code)

Downloads:

Package source: MRIreduce_1.0.0.tar.gz
Windows binaries: r-release: MRIreduce_1.0.0.zip, r-oldrel: MRIreduce_1.0.0.zip
macOS binaries: r-release (arm64): MRIreduce_1.0.0.tgz, r-oldrel (arm64): MRIreduce_1.0.0.tgz, r-release (x86_64): MRIreduce_1.0.0.tgz, r-oldrel (x86_64): MRIreduce_1.0.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=MRIreduce to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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