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MLML2R: Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions

Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) <doi:10.1093/bioinformatics/btt459> and Kiihl et al. (2019) <doi:10.1515/sagmb-2018-0031>.

Version: 0.3.3
Suggests: minfi, microbenchmark, GEOquery, knitr, rmarkdown, IlluminaHumanMethylation450kmanifest
Published: 2019-10-17
DOI: 10.32614/CRAN.package.MLML2R
Author: Samara Kiihl [aut, cre], Maria Jose Martinez-Garrido [aut], Arce Domingo-Relloso [aut], Jose Bermudez [aut], Maria Tellez-Plaza [aut]
Maintainer: Samara Kiihl <samara at ime.unicamp.br>
BugReports: https://github.com/samarafk/MLML2R/issues
License: MIT + file LICENSE
URL: https://github.com/samarafk/MLML2R
NeedsCompilation: no
Citation: MLML2R citation info
CRAN checks: MLML2R results

Documentation:

Reference manual: MLML2R.pdf
Vignettes: Using MLML2R

Downloads:

Package source: MLML2R_0.3.3.tar.gz
Windows binaries: r-devel: MLML2R_0.3.3.zip, r-release: MLML2R_0.3.3.zip, r-oldrel: MLML2R_0.3.3.zip
macOS binaries: r-release (arm64): MLML2R_0.3.3.tgz, r-oldrel (arm64): MLML2R_0.3.3.tgz, r-release (x86_64): MLML2R_0.3.3.tgz, r-oldrel (x86_64): MLML2R_0.3.3.tgz
Old sources: MLML2R archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=MLML2R to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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