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Electronic health records (EHR) linked with biorepositories are a powerful platform for translational studies. A major bottleneck exists in the ability to phenotype patients accurately and efficiently. Towards that end, we developed an automated high-throughput phenotyping method integrating International Classification of Diseases (ICD) codes and narrative data extracted using natural language processing (NLP). Specifically, our proposed method, called MAP (Map Automated Phenotyping algorithm), fits an ensemble of latent mixture models on aggregated ICD and NLP counts along with healthcare utilization. The MAP algorithm yields a predicted probability of phenotype for each patient and a threshold for classifying subjects with phenotype yes/no (See Katherine P. Liao, et al. (2019) <doi:10.1093/jamia/ocz066>.).
Version: | 1.0.0 |
Depends: | R (≥ 3.4.0), flexmix (≥ 2.3-14), Matrix (≥ 1.2-10) |
Imports: | magrittr |
Suggests: | knitr, pROC, rmarkdown, testthat |
Published: | 2024-12-02 |
DOI: | 10.32614/CRAN.package.MAP |
Author: | Thomas Charlon [aut, cre], Chuan Hong [aut], Jiehuan Sun [aut], Katherine Liao [aut], Sheng Yu [aut], Tianxi Cai [aut], PARSE Health [aut] (<https://parse-health.org>), CELEHS [aut] (<https://celehs.hms.harvard.edu>) |
Maintainer: | Thomas Charlon <charlon at protonmail.com> |
BugReports: | https://github.com/celehs/MAP/issues |
License: | GPL-3 |
URL: | https://celehs.github.io/MAP/ |
NeedsCompilation: | no |
Materials: | README |
CRAN checks: | MAP results |
Reference manual: | MAP.pdf |
Vignettes: |
MAP: Multimodal Automated Phenotyping (source) Simulated Example (source, R code) |
Package source: | MAP_1.0.0.tar.gz |
Windows binaries: | r-devel: MAP_1.0.0.zip, r-release: MAP_1.0.0.zip, r-oldrel: MAP_1.0.0.zip |
macOS binaries: | r-release (arm64): MAP_1.0.0.tgz, r-oldrel (arm64): MAP_1.0.0.tgz, r-release (x86_64): MAP_1.0.0.tgz, r-oldrel (x86_64): MAP_1.0.0.tgz |
Old sources: | MAP archive |
Reverse imports: | sureLDA |
Please use the canonical form https://CRAN.R-project.org/package=MAP to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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