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ImmuneSigR: Immune Cell Signature Retrieval and Single-Cell Scoring

Provides a literature-derived database of immune cell markers formatted as Gene Matrix Transposed (GMT) files. Users can search immune cell signatures, retrieve marker lists, export GMT files, create custom marker sets, and score gene-by-cell expression matrices with dependency-free rank-based or mean-expression methods. Cell subpopulations are distinguished by their source PMIDs. For the core curation of the lung cell atlas, see Travaglini et al. (2020) <doi:10.1038/s41586-020-2922-4>. For the pan-cancer B cell signatures, see Fitzsimons et al. (2024) <doi:10.1016/j.ccell.2024.09.011>.

Version: 0.1.0
Suggests: knitr, rmarkdown
Published: 2026-05-19
DOI: 10.32614/CRAN.package.ImmuneSigR
Author: Yingyan Liang [aut, cre], Peng Luo [aut]
Maintainer: Yingyan Liang <liangyingyan0625 at 163.com>
BugReports: https://github.com/YingYanLaing/ImmuneSigR/issues
License: GPL-3
URL: https://github.com/YingYanLaing/ImmuneSigR
NeedsCompilation: no
Materials: NEWS
CRAN checks: ImmuneSigR results

Documentation:

Reference manual: ImmuneSigR.html , ImmuneSigR.pdf
Vignettes: Introduction to ImmuneSigR (source, R code)

Downloads:

Package source: ImmuneSigR_0.1.0.tar.gz
Windows binaries: r-devel: ImmuneSigR_0.1.0.zip, r-release: ImmuneSigR_0.1.0.zip, r-oldrel: ImmuneSigR_0.1.0.zip
macOS binaries: r-release (arm64): ImmuneSigR_0.1.0.tgz, r-oldrel (arm64): ImmuneSigR_0.1.0.tgz, r-release (x86_64): ImmuneSigR_0.1.0.tgz, r-oldrel (x86_64): ImmuneSigR_0.1.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=ImmuneSigR to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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