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We consider a multiple testing procedure used in many modern applications which is the q-value method proposed by Storey and Tibshirani (2003), <doi:10.1073/pnas.1530509100>. The q-value method is based on the false discovery rate (FDR), hence versions of the q-value method can be defined depending on which estimator of the proportion of true null hypotheses, p0, is plugged in the FDR estimator. We implement the q-value method based on two classical pi0 estimators, and furthermore, we propose and implement three versions of the q-value method for homogeneous discrete uniform P-values based on pi0 estimators which take into account the discrete distribution of the P-values.
| Version: | 1.1 |
| Suggests: | coin, exactRankTests |
| Published: | 2020-04-01 |
| DOI: | 10.32614/CRAN.package.DiscreteQvalue |
| Author: | Marta Cousido Rocha [aut, cre], José Carlos Soage González [ctr], Jacobo de Uña Álvarez [aut, ths], Sebastian Döhler [aut] |
| Maintainer: | Marta Cousido Rocha <martacousido at uvigo.es> |
| License: | GPL-2 |
| NeedsCompilation: | no |
| CRAN checks: | DiscreteQvalue results |
| Reference manual: | DiscreteQvalue.pdf |
| Package source: | DiscreteQvalue_1.1.tar.gz |
| Windows binaries: | r-devel: DiscreteQvalue_1.1.zip, r-release: DiscreteQvalue_1.1.zip, r-oldrel: DiscreteQvalue_1.1.zip |
| macOS binaries: | r-release (arm64): DiscreteQvalue_1.1.tgz, r-oldrel (arm64): DiscreteQvalue_1.1.tgz, r-release (x86_64): DiscreteQvalue_1.1.tgz, r-oldrel (x86_64): DiscreteQvalue_1.1.tgz |
| Old sources: | DiscreteQvalue archive |
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