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This vignettes illustrate how our team prepared a submission for subchallenge 3.
The 'csv_file' is a file path of evaluation for subchallenge 3 given from the competition. Change the like with the one you would like to predict.
csv_file <- 'Data/subC3/SubC3_10K_0001_mutation_table.csv'
\dontrun{x <- read.table(csv_file, header = T, sep = ',', colClasses = "character")}
Initical state is '0', interval dropout is '-', point dropout is '' (point dropout was '' from the file, but we will replace it with ''), and mutational outcome states are 'A' to 'Z'.
\dontrun{states <- c('0', '-', '*', LETTERS)}
Read file and save it as 'phyDat' object.
\dontrun{tip_names <- x[, 1]}
\dontrun{x <- x[,-1]}
\dontrun{rownames(x) <- tip_names}
\dontrun{x[ x == '' ] = '*' ## specified * as point dropout (point missing)}
\dontrun{x = as.matrix(x)}
\dontrun{x <- x %>% phyDat(type = 'USER', levels = states)}
\dontrun{states2num = 1:length(states)}
\dontrun{names(states2num) = states}
We tried weighted hamming I and II with large number of parameter combinations, and found weighted hamming I with weight below worked fairly well.
InfoW = 1:5
InfoW[1] = 1 ## Score
InfoW[2] = .9
InfoW[3] = .4
InfoW[4:26] = 3
\dontrun{aTree2 <- x %>% dist_weighted_hamming(InfoW, FALSE) %>% fastme.ols()}
\dontrun{write.tree(aTree2, "Kwak_Gongsub3_submission.nw")}
Thanks!
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