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A systematic biology tool was developed to identify cell infiltration via an Individualized Cell crosstalk network. 'CITMIC' first constructed a weighted cell crosstalk network by integrating Cell-target interaction information, biological process data from the Gene Ontology (GO) database, and gene transcriptomic data in a specific sample, and then, it used a network propagation algorithm on the network to identify cell infiltration for the sample. Ultimately, cell infiltration in the patient dataset was obtained by normalizing the centrality scores of the cells.
| Version: | 0.1.2 |
| Depends: | R (≥ 2.10) |
| Imports: | fastmatch, igraph, parallel, stats |
| Suggests: | knitr, rmarkdown |
| Published: | 2024-11-08 |
| DOI: | 10.32614/CRAN.package.CITMIC |
| Author: | Junwei Han [aut, cre, cph], Xilong Zhao [aut] |
| Maintainer: | Junwei Han <hanjunwei1981 at 163.com> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | CITMIC results |
| Reference manual: | CITMIC.pdf |
| Vignettes: |
CITMIC User Guide (source, R code) |
| Package source: | CITMIC_0.1.2.tar.gz |
| Windows binaries: | r-devel: CITMIC_0.1.2.zip, r-release: CITMIC_0.1.2.zip, r-oldrel: CITMIC_0.1.2.zip |
| macOS binaries: | r-release (arm64): CITMIC_0.1.2.tgz, r-oldrel (arm64): CITMIC_0.1.2.tgz, r-release (x86_64): CITMIC_0.1.2.tgz, r-oldrel (x86_64): CITMIC_0.1.2.tgz |
| Old sources: | CITMIC archive |
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These binaries (installable software) and packages are in development.
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