BSET: A Bayesian Surrogate Evaluation Test

An implementation of the Bayesian Surrogate Evaluation Test (BSET) for assessing the validity of surrogate markers in clinical trials. Provides hypothesis testing tools to evaluate whether a surrogate can reliably estimate the causal effect of a treatment on a primary outcome. Implements the imputation-based Bayesian methodology of Carlotti and Parast (2026) <doi:10.48550/arXiv.2603.14381>, extending the frequentist rank-based approach of Parast et al. (2024) <doi:10.1093/biomtc/ujad035>. Addresses key limitations of the frequentist method, including the lack of causal interpretability and the inability to adjust for covariates in the estimation process.

Version:	1.0
Depends:	R (≥ 3.5)
Imports:	rstan, ggplot2, future, parallel, mvtnorm, dplyr, SurrogateRank, Rdpack, rlang
Suggests:	knitr, rmarkdown, bookdown
Published:	2026-05-22
DOI:	10.32614/CRAN.package.BSET (may not be active yet)
Author:	Pietro Carlotti [aut, cre], Layla Parast [aut]
Maintainer:	Pietro Carlotti <pietro.carlotti at utexas.edu>
BugReports:	https://github.com/PietroCarlotti/BSET/issues
License:	GPL-3
URL:	https://pietrocarlotti.github.io/BSET/, https://github.com/PietroCarlotti/BSET
NeedsCompilation:	no
Materials:	README
CRAN checks:	BSET results

Documentation:

Reference manual:	BSET.html , BSET.pdf
Vignettes:	BSET Tutorial (source, R code)

Downloads:

Package source:	BSET_1.0.tar.gz
Windows binaries:	r-devel: not available, r-release: BSET_1.0.zip, r-oldrel: BSET_1.0.zip
macOS binaries:	r-release (arm64): BSET_1.0.tgz, r-oldrel (arm64): BSET_1.0.tgz, r-release (x86_64): not available, r-oldrel (x86_64): not available

Linking:

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