BIGDAWG: Case-Control Analysis of Multi-Allelic Loci

Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.

Version:	3.0.3
Depends:	R (≥ 3.5.0)
Imports:	XML, httr, haplo.stats, parallel
Suggests:	knitr, rmarkdown
Published:	2021-11-17
DOI:	10.32614/CRAN.package.BIGDAWG
Author:	Derek Pappas, Steve Mack, Jill Hollenbach
Maintainer:	Steve Mack <Steven.Mack at ucsf.edu>
BugReports:	https://github.com/IgDAWG/BIGDAWG/issues
License:	GPL (≥ 3)
URL:	http://tools.immunogenomics.org/, https://github.com/IgDAWG/BIGDAWG
NeedsCompilation:	no
Materials:	NEWS
CRAN checks:	BIGDAWG results

Documentation:

Reference manual:	BIGDAWG.pdf
Vignettes:	BIGDAWG GLSconvert

Downloads:

Package source:	BIGDAWG_3.0.3.tar.gz
Windows binaries:	r-devel: BIGDAWG_3.0.3.zip, r-release: BIGDAWG_3.0.3.zip, r-oldrel: BIGDAWG_3.0.3.zip
macOS binaries:	r-release (arm64): BIGDAWG_3.0.3.tgz, r-oldrel (arm64): BIGDAWG_3.0.3.tgz, r-release (x86_64): BIGDAWG_3.0.3.tgz, r-oldrel (x86_64): BIGDAWG_3.0.3.tgz
Old sources:	BIGDAWG archive

Reverse dependencies:

Reverse imports:

pould, SSHAARP

Linking:

Please use the canonical form https://CRAN.R-project.org/package=BIGDAWG to link to this page.