<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Estimation for Binary Emax Models with Missing Responses and
Bias Reduction</dc:title>
  <dc:title>R package ememax version 0.1.0</dc:title>
  <dc:description>Provides estimation utilities for binary Emax dose-response models. Includes Expectation-Maximization based maximum likelihood estimation when the binary response is missing, as well as bias-reduced estimators including Jeffreys-penalized likelihood, Firth-score, and Cox-Snell corrections.The methodology is described in Zhang, Pradhan, and Zhao (2025) &lt;doi:10.1177/09622802251403356&gt; and Zhang, Pradhan, and Zhao (2026) &lt;doi:10.1080/10543406.2026.2627387&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 4.0.0), clinDR (&gt;= 2.5.2)</dc:relation>
  <dc:relation>Imports: BB, brglm, boot, formula.tools, MASS, maxLik, numDeriv, stats</dc:relation>
  <dc:relation>Suggests: knitr, rmarkdown, testthat (&gt;= 3.0.0)</dc:relation>
  <dc:creator>Jiangshan Zhang &lt;jiszhang@ucdavis.edu&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Jiangshan Zhang [aut, cre],
  Vivek Pradhan [aut],
  Yuxi Zhao [aut]</dc:contributor>
  <dc:rights>MIT + file LICENSE (https://CRAN.R-project.org/package=ememax/LICENSE)</dc:rights>
  <dc:date>2026-03-17</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=ememax</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.ememax</dc:identifier>
</oai_dc:dc>
