<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Automated Mendelian Randomization Workflows and Visualizations</dc:title>
  <dc:title>R package autoMR version 0.1.1</dc:title>
  <dc:description>Provides tools to summarize, analyze, and visualize results
    from Mendelian randomization studies using summarized genetic
    association data. The package includes functions for generating forest
    plots and scatter plots at the single-nucleotide polymorphism
    and Mendelian randomization method levels, and for fitting multiple
    estimators in a unified workflow, including inverse-variance weighted
    estimation, Mendelian randomization Egger regression,
    the weighted median estimator, the robust adjusted
    profile score, Mendelian randomization pleiotropy residual sum
    and outlier, Mendelian randomization with the genotype
    recoding invariance property, and a Bayesian horseshoe
    method. Related methods are described by Burgess (2013)
    &lt;doi:10.1002/gepi.21758&gt;, Bowden (2015) &lt;doi:10.1093/ije/dyv080&gt;,
    Bowden (2016) &lt;doi:10.1002/gepi.21965&gt;, Zhao (2020)
    &lt;doi:10.1214/19-AOS1866&gt;, Verbanck (2018)
    &lt;doi:10.1038/s41588-018-0099-7&gt;, Dudbridge (2025)
    &lt;doi:10.1371/journal.pgen.1011967&gt;, and Grant and Burgess (2024)
    &lt;doi:10.1016/j.ajhg.2023.12.002&gt;. Related open-source software
    includes 'TwoSampleMR' &lt;https://github.com/MRCIEU/TwoSampleMR&gt;,
    'mr.raps' &lt;https://github.com/qingyuanzhao/mr.raps&gt;,
    'MR-PRESSO' &lt;https://github.com/rondolab/MR-PRESSO&gt;, and
    'MR-Horse' &lt;https://github.com/aj-grant/mrhorse&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 4.2)</dc:relation>
  <dc:relation>Imports: ggplot2 (&gt;= 4.0.1), dplyr (&gt;= 1.1.4), tidyr (&gt;= 1.3.1),
MendelianRandomization (&gt;= 0.10.0), R2jags (&gt;= 0.8-9), coda (&gt;=
0.19-4.1), nortest (&gt;= 1.0-4), grDevices, graphics, stats,
utils, methods</dc:relation>
  <dc:creator>Kelin Zhong &lt;kelin.zhong@uconn.edu&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Kelin Zhong [aut, cre],
  Chia-Ling Kuo [aut]</dc:contributor>
  <dc:rights>GPL-3</dc:rights>
  <dc:date>2026-03-29</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=autoMR</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.autoMR</dc:identifier>
</oai_dc:dc>
