Sample Size Calculation for PICOT-Based Study Designs R package PICOTsize version 0.1.0 Provides sample size calculators for the study designs covered by the PICOT framework, including cross-sectional, case-control, cohort, superiority, non-inferiority, and equivalence clinical trials, and diagnostic test accuracy studies, following Bhardwaj et al. (2024) <doi:10.4103/jfmpc.jfmpc_1675_23>. Calculations are performed using the 'epiR' package as a validated computational backend. Includes a 'shiny' application with a PICOT-based design wizard, an interactive sensitivity plot, and automatically generated Methods-section text for manuscripts. Software Depends: R (>= 4.1.0) Imports: bslib, epiR, ggplot2, plotly, rlang, shiny Suggests: knitr, rmarkdown, testthat (>= 3.0.0) Atefeh Rashidi Pour <rashidiatefeh98@gmail.com> Comprehensive R Archive Network (CRAN) Atefeh Rashidi Pour [aut, cre] MIT + file LICENSE (https://CRAN.R-project.org/package=PICOTsize/LICENSE) 2026-10-10 application/tgz https://CRAN.R-project.org/package=PICOTsize doi:10.32614/CRAN.package.PICOTsize