Variable Selection via Cross-Validated Net Benefit R package NBvarsel version 0.1.1 Performs exhaustive or groupwise (backward elimination) variable selection for binary outcome prediction models using cross-validated Net Benefit as the optimization criterion. It supports predictor costs, restricted cubic splines, interaction terms, permutation importance, and parallel computation. It includes visualizations for model comparison and variable importance. References include Vickers AJ & Elkin EB (2006) <doi:10.1177/0272989X06295361>, Van Calster B et al. (2018) <doi:10.1016/j.eururo.2018.08.038>, Vickers AJ et al. (2019) <doi:10.1186/s41512-019-0064-7>, and Baker SG et al. (2012) <doi:10.1515/1557-4679.1395>. Software Depends: R (>= 4.1.0) Imports: caret, DescTools, doParallel, dplyr, foreach, ggplot2, ggtext, parallel, patchwork, pROC, rlang, rms, scales, stats, stringr, tidyr Suggests: glmnet, ggsci, gt, knitr, quarto, testthat (>= 3.0.0) Lasai Barreñada <lasai.barrenadataleb@kuleuven.be> Comprehensive R Archive Network (CRAN) Lasai Barreñada [aut, cre] (ORCID: <https://orcid.org/0000-0001-8020-0210>, Department of Development and Regeneration ; Leuven Unit for Health Technology Assessment Research (LUHTAR), KU Leuven, Belgium), Laure Wynants [aut] (ORCID: <https://orcid.org/0000-0002-3037-122X>, Department of Development and Regeneration, KU Leuven, Belgium; Leuven Unit for Health Technology Assessment Research (LUHTAR), KU Leuven, Belgium; Department of Epidemiology, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, Netherlands), Ewout W. Steyerberg [aut] (ORCID: <https://orcid.org/0000-0002-7787-0122>, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, Netherlands), Andrew Vickers [aut] (ORCID: <https://orcid.org/0000-0003-1525-6503>, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA), Ben Van Calster [aut] (ORCID: <https://orcid.org/0000-0003-1613-7450>, Department of Development and Regeneration, KU Leuven, Belgium; Leuven Unit for Health Technology Assessment Research (LUHTAR), KU Leuven, Belgium; Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, Netherlands) GPL (>= 3) 2026-08-30 application/tgz https://CRAN.R-project.org/package=NBvarsel doi:10.32614/CRAN.package.NBvarsel