Mathematical Utilities for MALDI-TOF Mass Spectrometry R package MALDIassist version 1.0.2 Supports matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry workflows from raw Bruker spectra to cohort-level peak matrices. Provides spectrum loading, Savitzky-Golay smoothing, baseline correction (SNIP and TopHat), Gaussian kernel-regression-based peak detection including shoulder peaks, peak-quality assessment, filtering, and cohort feature analysis. Computationally intensive routines are implemented in C++ using 'Rcpp'. The implemented signal-processing methods include those described by Savitzky and Golay (1964) <doi:10.1021/ac60214a047>, Ryan et al. (1988) <doi:10.1016/0168-583X(88)90063-8>, Stanford, Bagley and Solomon (2016) <doi:10.1186/s12953-016-0107-8>, and Nadaraya-Watson kernel regression (Nadaraya (1964) <doi:10.1137/1109020>; Watson (1964) <https://www.jstor.org/stable/25049340>). Software Depends: R (>= 4.1.0) Imports: Rcpp, gtools LinkingTo: Rcpp Suggests: colorspace, pheatmap, testthat (>= 3.0.0) Wonseok Oh <hiows97@gmail.com> Comprehensive R Archive Network (CRAN) Wonseok Oh [aut, cre] (ORCID: <https://orcid.org/0009-0002-0687-8466>) MIT + file LICENSE (https://CRAN.R-project.org/package=MALDIassist/LICENSE) 2026-08-04 application/tgz https://CRAN.R-project.org/package=MALDIassist doi:10.32614/CRAN.package.MALDIassist