<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Estimate Location-Scale Joint Models</dc:title>
  <dc:title>R package LSJM version 0.1.0</dc:title>
  <dc:description>Estimation of mixed models including a subject-specific variance 
    that can be time- and covariate-dependent or defined for within- and 
    between-visit variability. In the joint modeling framework, the package 
    handles left truncation, interval censoring, and multistate models, and 
    allows a flexible dependence structure between competing events and the 
    longitudinal marker. Estimation is performed in a frequentist framework 
    using the Marquardt-Levenberg algorithm. Methods are described in 
    Courcoul et al. (2025) &lt;doi:10.1002/sim.70244&gt; and in Courcoul et al. (2026) 
    &lt;doi:10.1002/bimj.70123&gt;.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 3.5.0)</dc:relation>
  <dc:relation>Imports: Rcpp, marqLevAlg, survival, flexsurv, ggplot2, splines,
spacefillr, survminer, foreach, doParallel, SmoothHazard,
parallel, mvtnorm, dplyr</dc:relation>
  <dc:relation>LinkingTo: Rcpp, RcppArmadillo</dc:relation>
  <dc:creator>Léonie Courcoul &lt;courcoul.leonie498@gmail.com&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Léonie Courcoul [aut, cre],
  Antoine Barbieri [aut],
  Hélène Jacqmin-Gadda [aut]</dc:contributor>
  <dc:rights>GPL (&gt;= 2)</dc:rights>
  <dc:date>2026-08-04</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=LSJM</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.LSJM</dc:identifier>
</oai_dc:dc>
