<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Calculators for Insulin and Glucagon Release Indices</dc:title>
  <dc:title>R package IsletCalc version 0.0.1</dc:title>
  <dc:description>Facilitates the calculation of validated pancreatic islet
    hormone-release indices from fasting and oral glucose tolerance test
    (OGTT) measurements. Provides beta-cell insulin release indices
    (including HOMA-beta, corrected insulin response, Stumvoll first-phase
    index, BIGTT-AIR, and disposition indices) as described in
    Madsen (2024) &lt;doi:10.1038/s42255-024-01140-6&gt;, alongside alpha-cell
    glucagon release and glucagon resistance indices derived from the
    glucagon-suppression and liver-alpha-cell-axis literature. Enables
    reproducible assessment of beta-cell and alpha-cell function for
    metabolic and endocrine research.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 3.5.0)</dc:relation>
  <dc:relation>Suggests: knitr, rmarkdown, spelling, testthat (&gt;= 3.0.0)</dc:relation>
  <dc:creator>Sufyan Suleman &lt;sufyansuleman@hotmail.com&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Sufyan Suleman [aut, cre] (ORCID:
    &lt;https://orcid.org/0000-0001-6612-6915&gt;)</dc:contributor>
  <dc:rights>MIT + file LICENSE (https://CRAN.R-project.org/package=IsletCalc/LICENSE)</dc:rights>
  <dc:date>2026-07-16</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=IsletCalc</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.IsletCalc</dc:identifier>
  <dc:language>en-US</dc:language>
</oai_dc:dc>
