Transcriptional Disruption Score for Gene Sets R package DSGEr version 1.3.1 Computes pathway-level transcriptional disruption scores from differential expression p-values using permutation tests with Generalized Pareto Distribution (GPD) tail extrapolation and false discovery rate (FDR) correction. Reference: Guo P, Li H (2026) DSGE: Disruption Score of Gene Expression for Gene-Set Enrichment Analysis. <https://github.com/LHJLab/DSGE>. Software Imports: data.table, evd, methods, POT, Rcpp LinkingTo: Rcpp Suggests: AnnotationDbi, GO.db Enhances: KEGGREST, org.Hs.eg.db, reactome.db Pingwei Guo <1489413126@qq.com> Comprehensive R Archive Network (CRAN) Pingwei Guo [aut, cre], Huijuan Li [aut] MIT + file LICENSE (https://CRAN.R-project.org/package=DSGEr/LICENSE) 2026-06-30 application/tgz https://CRAN.R-project.org/package=DSGEr doi:10.32614/CRAN.package.DSGEr