<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Nonlinear Causal Dose-Response Estimation via Splines</dc:title>
  <dc:title>R package CausalSpline version 0.1.0</dc:title>
  <dc:description>Estimates nonlinear causal dose-response functions for continuous
    treatments using spline-based methods under standard causal assumptions
    (unconfoundedness / ignorability). Implements three identification
    strategies: Inverse Probability Weighting (IPW) via the generalised
    propensity score (GPS), G-computation (outcome regression), and a
    doubly-robust combination. Natural cubic splines and B-splines are
    supported for both the exposure-response curve f(T) and the propensity
    nuisance model. Pointwise confidence bands are obtained via the sandwich
    estimator or nonparametric bootstrap. Also provides fragility diagnostics
    including pointwise curvature-based fragility, uncertainty-normalised
    fragility, and regional integration over user-defined treatment intervals.
    Builds on the framework of Hirano and Imbens (2004)
    &lt;doi:10.1111/j.1468-0262.2004.00481.x&gt; for continuous treatments and
    extends it to fully nonparametric spline estimation.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 4.1.0)</dc:relation>
  <dc:relation>Imports: splines, stats, utils, ggplot2 (&gt;= 3.4.0), sandwich, boot</dc:relation>
  <dc:relation>Suggests: testthat (&gt;= 3.0.0), knitr, rmarkdown, patchwork, cobalt,
dplyr</dc:relation>
  <dc:creator>Subir Hait &lt;haitsubi@msu.edu&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Subir Hait [aut, cre] (ORCID: &lt;https://orcid.org/0009-0004-9871-9677&gt;)</dc:contributor>
  <dc:rights>GPL (&gt;= 3)</dc:rights>
  <dc:date>2026-03-25</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=CausalSpline</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.CausalSpline</dc:identifier>
</oai_dc:dc>
