Package: rbmi
Title: Reference Based Multiple Imputation
Version: 1.6.1
Authors@R: c(
    person("Lukas A.", "Widmer", email = "lukas_andreas.widmer@novartis.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0003-1471-3493")),
    person("Craig", "Gower-Page", email = "craig.gower-page@novartis.com", role = c("aut")),
    person("Isaac", "Gravestock", email = "isaac.gravestock@roche.com", role = c("aut"), comment = c(ORCID = "0000-0003-0283-2065")),
    person("Alessandro", "Noci", email = "alessandro.noci@roche.com", role = c("aut")),
    person("Marcel", "Wolbers", email = "marcel.wolbers@bayer.com", role = "aut", comment = c(ORCID = "0000-0003-4915-9015")),
    person("Daniel", "Sabanes Bove", email = "daniel.sabanes_bove@rconis.com", role = c("aut"), comment = c(ORCID = "0000-0002-0176-9239")),
    person("F. Hoffmann-La Roche AG", role = c("cph", "fnd"))
    )
Description: Implements standard and reference based multiple imputation methods for continuous
    longitudinal endpoints (Gower-Page et al. (2022) <doi:10.21105/joss.04251>). In particular,
    this package supports deterministic conditional mean imputation and jackknifing as described
    in Wolbers et al.  (2022) <doi:10.1002/pst.2234>, Bayesian multiple imputation as described
    in Carpenter et al. (2013) <doi:10.1080/10543406.2013.834911>, and bootstrapped maximum
    likelihood imputation as described in von Hippel and Bartlett (2021) <doi:10.1214/20-STS793>.
Encoding: UTF-8
LazyData: true
URL: https://openpharma.github.io/rbmi/,
        https://github.com/openpharma/rbmi
BugReports: https://github.com/openpharma/rbmi/issues
RoxygenNote: 8.0.0
Suggests: dplyr, tidyr, nlme, testthat, emmeans, tibble, mvtnorm,
        knitr, rmarkdown, bookdown, lubridate, purrr, ggplot2, rstan
        (>= 2.26.0), R.rsp, withr, spelling
Config/testthat/edition: 3
Imports: mmrm, pkgload, Matrix, tools, methods, R6, assertthat, jinjar,
        fs, stringr, lifecycle
Depends: R (>= 3.4.0)
License: Apache License (>= 2)
VignetteBuilder: R.rsp
Language: en-GB
Config/roxygen2/version: 8.0.0
NeedsCompilation: no
Packaged: 2026-07-22 18:59:47 UTC; widmelu1
Author: Lukas A. Widmer [aut, cre] (ORCID:
    <https://orcid.org/0000-0003-1471-3493>),
  Craig Gower-Page [aut],
  Isaac Gravestock [aut] (ORCID: <https://orcid.org/0000-0003-0283-2065>),
  Alessandro Noci [aut],
  Marcel Wolbers [aut] (ORCID: <https://orcid.org/0000-0003-4915-9015>),
  Daniel Sabanes Bove [aut] (ORCID:
    <https://orcid.org/0000-0002-0176-9239>),
  F. Hoffmann-La Roche AG [cph, fnd]
Maintainer: Lukas A. Widmer <lukas_andreas.widmer@novartis.com>
Repository: CRAN
Date/Publication: 2026-07-22 21:30:02 UTC
Built: R 4.6.0; ; 2026-07-22 22:42:29 UTC; unix
