Package: easyLSEA
Title: Lipid Set Enrichment Analysis with Dual KS and 'fgsea' Engines
Version: 0.2.1
Authors@R: 
    person("David", "Guardamino Ojeda",
           role = c("aut", "cre"),
           email = "david.guardamino@gmail.com",
           comment = c(ORCID = "0000-0002-3122-2218"))
Description: Provides biology-aware lipid set enrichment analysis (LSEA)
    for lipidomics data using dual engines: the Kolmogorov-Smirnov test
    and the fast gene set enrichment algorithm from the 'fgsea' package.
    Annotates lipids into biological groups at three levels (lipid class,
    LIPID MAPS category, functional category) and tests for coordinated
    directional shifts between conditions. Includes fatty acid chain
    analysis with trend plots weighted by lipid abundance (Spearman rank
    correlation, configurable smoothing), wide-format chain position
    output (sn-1, sn-2, sn-3, sn-4), annotation confidence filtering, and
    export utilities for reproducible reporting in CSV, 'Excel', and PDF
    formats. Vignettes are available in English and Spanish. Methods are
    based on Subramanian et al. (2005) <doi:10.1073/pnas.0506580102> and
    Korotkevich et al. (2021) <doi:10.1101/060012>.
License: MIT + file LICENSE
Encoding: UTF-8
Depends: R (>= 4.1.0)
RoxygenNote: 8.0.0
Imports: ggplot2, withr
Suggests: fgsea, knitr, openxlsx, rmarkdown, spelling, testthat (>=
        3.0.0)
URL: https://github.com/DavidGO464/easyLSEA
BugReports: https://github.com/DavidGO464/easyLSEA/issues
LazyData: true
Config/testthat/edition: 3
VignetteBuilder: knitr
Language: en-US
NeedsCompilation: no
Packaged: 2026-06-08 17:35:46 UTC; david_md
Author: David Guardamino Ojeda [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-3122-2218>)
Maintainer: David Guardamino Ojeda <david.guardamino@gmail.com>
Repository: CRAN
Date/Publication: 2026-06-16 19:40:02 UTC
Built: R 4.6.0; ; 2026-06-16 23:26:46 UTC; unix
