Flexible Simulation Utilities for Pharmacometric Modeling


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Documentation for package ‘amp.sim’ version 0.1.0

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convert_nmsyntax Convert NONMEM specific syntax to R syntax
convert_nonmem Convert NONMEM model to R syntax
conv_pow Convert infix power notation to prefix notation
cut_equal cut function for (appr.) equal intervals
dose_func Create data.frame with dosing for usage in simulation with deSolve
dput2 Wrapper function around dput to provide more options
get_est Get model estimates from NONMEM ext or model file
get_inits get the initial states for the differential equations
get_nmblock Get information from dollar blocks inside NONMEM control streams
get_param Get parameter values from model or ext file
get_parmvar Get the variables within a NONMEM model that should be passed to the simulation model
make_nmsimmodel Create a simulation model from original model
mdose Performs multiple dosing in case of analytical solution of model
mod2shiny Creates a basic simulation app for a given R model
model_validation Validates NONMEM estimation model with an mrgsolve simulation model
nmlistblock convert a block to a list
overlaying Performs overlaying of simulations
par_delete Delete parenthesis including a numeric within a vector
pos_clpar Get position of closing parenthesis
sample_par Sample model parameters from a multivariate normal distribution
sample_sim Sample model parameters for a simulation
settings2df Add settings to dataframe
simdata Create a simulation dataset for NONMEM simulation
split_sim Split a large NONMEM simulation in chunks
tmpl_model Get coding for template models