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trialdiff: Clinical Trial Data-Cut Change Detection and Impact Assessment

A transparent, rule-based framework for detecting changes between successive data cuts of clinical trial datasets, classifying those changes into clinically meaningful categories, tracing user-defined data lineage, and assessing which downstream analyses and outputs may be affected. The package is designed to complement existing low-level data frame comparison tools by adding clinical-trial-specific classification, lineage and impact-assessment layers on top of deterministic comparison. The rule-based classification is similar in spirit to the data validation infrastructure of van der Loo and de Jonge (2021) <doi:10.18637/jss.v097.i10>.

Version: 0.2.0
Depends: R (≥ 4.1)
Imports: cli, dplyr, htmltools, jsonlite, rlang, tibble
Suggests: admiral, cards, covr, diffdf, haven, igraph, knitr, lintr, metacore, pharmaverseadam, pharmaversesdtm, pkgdown, rmarkdown, rtables, styler, tern, testthat (≥ 3.0.0), waldo, withr
Published: 2026-09-27
DOI: 10.32614/CRAN.package.trialdiff
Author: Hirujan Rangaraj [aut, cre]
Maintainer: Hirujan Rangaraj <hirujanrangaraj at gmail.com>
BugReports: https://github.com/Hirujan-R/trialdiff/issues
License: MIT + file LICENSE
URL: https://github.com/Hirujan-R/trialdiff, https://Hirujan-R.github.io/trialdiff/
NeedsCompilation: no
Language: en-GB
Materials: README, NEWS
CRAN checks: trialdiff results

Documentation:

Reference manual: trialdiff.html , trialdiff.pdf
Vignettes: Case study: data-cut review on public ADaM data (source, R code)
The change-classification system (source, R code)
trialdiff and the existing ecosystem (source, R code)
Lineage and impact assessment (source, R code)
Getting started with trialdiff (source, R code)

Downloads:

Package source: trialdiff_0.2.0.tar.gz
Windows binaries: r-devel: trialdiff_0.2.0.zip, r-release: trialdiff_0.2.0.zip, r-oldrel: trialdiff_0.2.0.zip
macOS binaries: r-release (arm64): trialdiff_0.2.0.tgz, r-oldrel (arm64): trialdiff_0.2.0.tgz, r-release (x86_64): trialdiff_0.2.0.tgz, r-oldrel (x86_64): trialdiff_0.2.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=trialdiff to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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