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nlmixr2auto: Automated Population Pharmacokinetic Modeling

Automated population pharmacokinetic modeling framework for data-driven initialisation, model evaluation, and metaheuristic optimization. Supports genetic algorithms, ant colony optimization, tabu search, and stepwise procedures for automated model selection and parameter estimation within the nlmixr2 ecosystem.

Version: 1.0.0
Depends: R (≥ 4.1.0), nlmixr2data
Imports: nlmixr2, nlmixr2est, nlmixr2autoinit, rxode2, dplyr, progressr, processx (> 3.8.0), withr, crayon
Published: 2026-02-06
DOI: 10.32614/CRAN.package.nlmixr2auto
Author: Zhonghui Huang [aut, cre], Joseph Standing [ctb], Matthew Fidler [ctb], Frank Kloprogge [ctb]
Maintainer: Zhonghui Huang <huangzhonghui22 at gmail.com>
BugReports: https://github.com/ucl-pharmacometrics/nlmixr2auto/issues
License: GPL (≥ 3)
URL: https://github.com/ucl-pharmacometrics/nlmixr2auto
NeedsCompilation: no
Language: en-US
CRAN checks: nlmixr2auto results

Documentation:

Reference manual: nlmixr2auto.html , nlmixr2auto.pdf

Downloads:

Package source: nlmixr2auto_1.0.0.tar.gz
Windows binaries: r-devel: nlmixr2auto_1.0.0.zip, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): nlmixr2auto_1.0.0.tgz, r-oldrel (arm64): nlmixr2auto_1.0.0.tgz, r-release (x86_64): nlmixr2auto_1.0.0.tgz, r-oldrel (x86_64): nlmixr2auto_1.0.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=nlmixr2auto to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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