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PRSPGx: Construct PGx PRS

Construct pharmacogenomics (PGx) polygenic risk score (PRS) with PRS-PGx-Unadj (unadjusted), PRS-PGx-CT (clumping and thresholding), PRS-PGx-L, -GL, -SGL (penalized regression), PRS-PGx-Bayes (Bayesian regression). Package is based on ”Pharmacogenomics Polyenic Risk Score for Drug Response Prediction Using PRS-PGx Methods” by Zhai, S., Zhang, H., Mehrotra, D.V., and Shen, J., 2021 (submitted).

Version: 0.3.0
Depends: R (≥ 4.0.0)
Imports: gglasso (≥ 1.5.0), SGL (≥ 1.3.0), glmnet (≥ 4.0.2), bigsnpr (≥ 1.5.2), Matrix (≥ 1.2.18), GIGrvg (≥ 0.5.0), MCMCpack (≥ 1.4.6), bdsmatrix (≥ 1.3.4), bigsparser (≥ 0.4.0), lmtest (≥ 0.9.37), mvtnorm (≥ 1.1.0), propagate (≥ 1.0.6), bigparallelr (≥ 0.2.3), methods (≥ 3.6.3), bigstatsr (≥ 1.2.3), Rfast (≥ 1.9.9), matrixcalc (≥ 1.0-3)
Suggests: knitr, rmarkdown
Published: 2022-07-20
Author: Song Zhai [aut, cre]
Maintainer: Song Zhai <zsviolet1993 at gmail.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
CRAN checks: PRSPGx results

Documentation:

Reference manual: PRSPGx.pdf
Vignettes: Put the title of your vignette here

Downloads:

Package source: PRSPGx_0.3.0.tar.gz
Windows binaries: r-devel: PRSPGx_0.3.0.zip, r-release: PRSPGx_0.3.0.zip, r-oldrel: PRSPGx_0.3.0.zip
macOS binaries: r-release (arm64): PRSPGx_0.3.0.tgz, r-oldrel (arm64): PRSPGx_0.3.0.tgz, r-release (x86_64): PRSPGx_0.3.0.tgz, r-oldrel (x86_64): PRSPGx_0.3.0.tgz
Old sources: PRSPGx archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=PRSPGx to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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