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EnvNJ: Whole Genome Phylogenies Using Sequence Environments
Contains utilities for the analysis of protein sequences in a phylogenetic context.
Allows the generation of phylogenetic trees base on protein sequences in an alignment-independent way.
Two different methods have been implemented. One approach is based on the frequency analysis of n-grams,
previously described in Stuart et al. (2002) <doi:10.1093/bioinformatics/18.1.100>. The other approach is based on the species-specific neighborhood preference around amino acids. Features include the conversion of a protein set into a vector
reflecting these neighborhood preferences, pairwise distances (dissimilarity) between these vectors,
and the generation of trees based on these distance matrices.
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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