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DrugSim2DR: Predict Drug Functional Similarity to Drug Repurposing

A systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. 'DrugSim2DR' first predict drug-drug functional similarity in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.

Version: 0.1.1
Depends: R (≥ 3.6)
Imports: igraph, stats, pheatmap, ChemmineR, rvest, base, sp, tidyr, reshape2, fastmatch
Suggests: knitr, rmarkdown
Published: 2023-08-10
Author: Junwei Han [aut, cre, cph], Ji Li [aut], Jiashuo Wu [aut]
Maintainer: Junwei Han <hanjunwei1981 at 163.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: DrugSim2DR results

Documentation:

Reference manual: DrugSim2DR.pdf
Vignettes: DrugSim2DR User Guide

Downloads:

Package source: DrugSim2DR_0.1.1.tar.gz
Windows binaries: r-devel: DrugSim2DR_0.1.1.zip, r-release: DrugSim2DR_0.1.1.zip, r-oldrel: DrugSim2DR_0.1.1.zip
macOS binaries: r-release (arm64): DrugSim2DR_0.1.1.tgz, r-oldrel (arm64): DrugSim2DR_0.1.1.tgz, r-release (x86_64): DrugSim2DR_0.1.1.tgz, r-oldrel (x86_64): DrugSim2DR_0.1.1.tgz
Old sources: DrugSim2DR archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=DrugSim2DR to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.
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