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A workflow to generate and analyze signatures based on copy number data using non-negative matrix factorization (NMF) in an approach similar to that used in mutational signatures. It can be used to extract features from Copy number segment data and use that to find a subset of copy number signatures which can be further used to correlate with other relevant data. For more on 'NMF' see Gaujoux (2013) <doi:10.1186/1471-2105-11-367>.
| Version: | 0.1.0 |
| Depends: | R (≥ 2.10), NMF |
| Imports: | methods, doParallel, foreach, flexmix, limSolve, ggplot2, snow, cowplot, pheatmap, RColorBrewer, viridisLite, colorspace, stats, utils |
| Suggests: | knitr, rmarkdown |
| Published: | 2026-01-08 |
| DOI: | 10.32614/CRAN.package.CNSigs (may not be active yet) |
| Author: | David Tallman [aut], Shawn Striker [cre, ctb], Daniel Stover [cph] |
| Maintainer: | Shawn Striker <striker.35 at osu.edu> |
| License: | MIT + file LICENSE |
| NeedsCompilation: | no |
| CRAN checks: | CNSigs results |
| Reference manual: | CNSigs.html , CNSigs.pdf |
| Vignettes: |
CNSigs.Rnw (source, R code) |
| Package source: | CNSigs_0.1.0.tar.gz |
| Windows binaries: | r-devel: CNSigs_0.1.0.zip, r-release: not available, r-oldrel: CNSigs_0.1.0.zip |
| macOS binaries: | r-release (arm64): CNSigs_0.1.0.tgz, r-oldrel (arm64): CNSigs_0.1.0.tgz, r-release (x86_64): CNSigs_0.1.0.tgz, r-oldrel (x86_64): CNSigs_0.1.0.tgz |
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These binaries (installable software) and packages are in development.
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