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CRAN Package Check Results for Package GMMAT

Last updated on 2026-09-26 05:50:37 CEST.

Flavor Version Tinstall Tcheck Ttotal Status Flags
r-devel-linux-x86_64-debian-clang 1.5.0 46.20 244.93 291.13 OK
r-devel-linux-x86_64-debian-gcc 1.5.0 38.73 206.56 245.29 OK
r-devel-linux-x86_64-fedora-clang 1.5.0 29.00 153.51 182.51 OK
r-devel-linux-x86_64-fedora-gcc 1.5.0 42.00 162.06 204.06 OK
r-devel-windows-x86_64 1.5.0 70.00 388.00 458.00 OK
r-patched-linux-x86_64 1.5.0 51.93 241.79 293.72 OK
r-release-linux-x86_64 1.5.0 51.95 232.79 284.74 OK
r-release-macos-arm64 1.5.0 12.00 90.00 102.00 OK
r-release-macos-x86_64 1.5.0 38.00 405.00 443.00 OK
r-release-windows-x86_64 1.5.0 70.00 310.00 380.00 OK
r-oldrel-macos-arm64 1.5.0 16.00 79.00 95.00 ERROR
r-oldrel-macos-x86_64 1.5.0 41.00 551.00 592.00 OK
r-oldrel-windows-x86_64 1.5.0 89.00 394.00 483.00 OK

Check Details

Version: 1.5.0
Check: tests
Result: ERROR Running ‘testthat.R’ [2s/2s] Running the tests in ‘tests/testthat.R’ failed. Complete output: > library(testthat) > library(GMMAT) > Sys.setenv(MKL_NUM_THREADS = 1) > > test_check("GMMAT") *** caught segfault *** address 0x110, cause 'invalid permissions' *** caught segfault *** address 0x110, cause 'invalid permissions' Traceback: 1: eval(c.expr, envir = args, enclos = envir) 2: eval(c.expr, envir = args, enclos = envir) 3: doTryCatch(return(expr), name, parentenv, handler) 4: tryCatchOne(expr, names, parentenv, handlers[[1L]]) 5: tryCatchList(expr, classes, parentenv, handlers) 6: tryCatch(eval(c.expr, envir = args, enclos = envir), error = function(e) e) 7: FUN(X[[i]], ...) 8: lapply(X = S, FUN = FUN, ...) 9: doTryCatch(return(expr), name, parentenv, handler) 10: tryCatchOne(expr, names, parentenv, handlers[[1L]]) 11: tryCatchList(expr, classes, parentenv, handlers) 12: tryCatch(expr, error = function(e) { call <- conditionCall(e) if (!is.null(call)) { if (identical(call[[1L]], quote(doTryCatch))) call <- sys.call(-4L) dcall <- deparse(call, nlines = 1L) prefix <- paste("Error in", dcall, ": ") LONG <- 75L sm <- strsplit(conditionMessage(e), "\n")[[1L]] w <- 14L + nchar(dcall, type = "w") + nchar(sm[1L], type = "w") if (is.na(w)) w <- 14L + nchar(dcall, type = "b") + nchar(sm[1L], type = "b") if (w > LONG) prefix <- paste0(prefix, "\n ") } else prefix <- "Error : " msg <- paste0(prefix, conditionMessage(e), "\n") .Internal(seterrmessage(msg[1L])) if (!silent && isTRUE(getOption("show.error.messages"))) { cat(msg, file = outFile) .Internal(printDeferredWarnings()) } invisible(structure(msg, class = "try-error", condition = e))}) 13: try(lapply(X = S, FUN = FUN, ...), silent = TRUE) 14: sendMaster(try(lapply(X = S, FUN = FUN, ...), silent = TRUE)) 15: FUN(X[[i]], ...) 16: lapply(seq_len(cores), inner.do) 17: mclapply(argsList, FUN, mc.preschedule = preschedule, mc.set.seed = set.seed, mc.silent = silent, mc.cores = cores) 18: e$fun(obj, substitute(ex), parent.frame(), e$data) 19: foreach(i = 1:ncores) %dopar% { if (!is.null(obj$P)) { if (bgenInfo$LayoutFlag == 2) { .Call(C_glmm_score_bgen13, as.numeric(res), obj$P, infile, paste0(outfile, "_tmp.", i), center2, MAF.range[1], MAF.range[2], miss.cutoff, miss.method, nperbatch, select, threadInfo$begin[i], threadInfo$end[i], threadInfo$pos[i], bgenInfo$N, bgenInfo$CompressionFlag, 1) } else { .Call(C_glmm_score_bgen11, as.numeric(res), obj$P, infile, paste0(outfile, "_tmp.", i), center2, MAF.range[1], MAF.range[2], miss.cutoff, miss.method, nperbatch, select, threadInfo$begin[i], threadInfo$end[i], threadInfo$pos[i], bgenInfo$N, bgenInfo$CompressionFlag, 1) } } else { if (bgenInfo$LayoutFlag == 2) { .Call(C_glmm_score_bgen13_sp, as.numeric(res), obj$Sigma_i, obj$Sigma_iX, obj$cov, infile, paste0(outfile, "_tmp.", i), center2, MAF.range[1], MAF.range[2], miss.cutoff, miss.method, nperbatch, select, threadInfo$begin[i], threadInfo$end[i], threadInfo$pos[i], bgenInfo$N, bgenInfo$CompressionFlag, 1) } else { .Call(C_glmm_score_bgen11_sp, as.numeric(res), obj$Sigma_i, obj$Sigma_iX, obj$cov, infile, paste0(outfile, "_tmp.", i), center2, MAF.range[1], MAF.range[2], miss.cutoff, miss.method, nperbatch, select, threadInfo$begin[i], threadInfo$end[i], threadInfo$pos[i], bgenInfo$N, bgenInfo$CompressionFlag, 1) } }} 20: glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, outfile = obj1.outfile.bgen.noselect.1.tmp, ncores = 2) 21: eval(code, test_env) 22: eval(code, test_env) 23: withCallingHandlers({ eval(code, test_env) new_expectations <- the$test_expectations > starting_expectations if (snapshot_skipped) { skip("On CRAN") } else if (!new_expectations && skip_on_empty) { skip_empty() }}, expectation = handle_expectation, packageNotFoundError = function(e) { if (on_cran()) { skip(paste0("{", e$package, "} is not installed.")) }}, snapshot_on_cran = function(cnd) { snapshot_skipped <<- TRUE invokeRestart("muffle_cran_snapshot")}, skip = handle_skip, warning = handle_warning, message = handle_message, error = handle_error, interrupt = handle_interrupt) 24: doTryCatch(return(expr), name, parentenv, handler) 25: tryCatchOne(expr, names, parentenv, handlers[[1L]]) 26: tryCatchList(expr, classes, parentenv, handlers) 27: tryCatch(withCallingHandlers({ eval(code, test_env) new_expectations <- the$test_expectations > starting_expectations if (snapshot_skipped) { skip("On CRAN") } else if (!new_expectations && skip_on_empty) { skip_empty() }}, expectation = handle_expectation, packageNotFoundError = function(e) { if (on_cran()) { skip(paste0("{", e$package, "} is not installed.")) }}, snapshot_on_cran = function(cnd) { snapshot_skipped <<- TRUE invokeRestart("muffle_cran_snapshot")}, skip = handle_skip, warning = handle_warning, message = handle_message, error = handle_error, interrupt = handle_interrupt), error = handle_fatal) 28: doWithOneRestart(return(expr), restart) 29: withOneRestart(expr, restarts[[1L]]) 30: withRestarts(tryCatch(withCallingHandlers({ eval(code, test_env) new_expectations <- the$test_expectations > starting_expectations if (snapshot_skipped) { skip("On CRAN") } else if (!new_expectations && skip_on_empty) { skip_empty() }}, expectation = handle_expectation, packageNotFoundError = function(e) { if (on_cran()) { skip(paste0("{", e$package, "} is not installed.")) }}, snapshot_on_cran = function(cnd) { snapshot_skipped <<- TRUE invokeRestart("muffle_cran_snapshot")}, skip = handle_skip, warning = handle_warning, message = handle_message, error = handle_error, interrupt = handle_interrupt), error = handle_fatal), end_test = function() { }) 31: test_code(code, parent.frame()) 32: test_that("cross-sectional id le 400 binomial", { plinkfiles <- strsplit(system.file("extdata", "geno.bed", package = "GMMAT"), ".bed", fixed = TRUE)[[1]] bgenfile <- system.file("extdata", "geno.bgen", package = "GMMAT") samplefile <- system.file("extdata", "geno.sample", package = "GMMAT") gdsfile <- system.file("extdata", "geno.gds", package = "GMMAT") txtfile <- system.file("extdata", "geno.txt", package = "GMMAT") txtfile1 <- system.file("extdata", "geno.txt.gz", package = "GMMAT") txtfile2 <- system.file("extdata", "geno.txt.bz2", package = "GMMAT") data(example) suppressWarnings(RNGversion("3.5.0")) set.seed(123) pheno <- rbind(example$pheno, example$pheno[1:100, ]) pheno$id <- 1:500 pheno$disease[sample(1:500, 20)] <- NA pheno$age[sample(1:500, 20)] <- NA pheno$sex[sample(1:500, 20)] <- NA pheno <- pheno[sample(1:500, 450), ] pheno <- pheno[pheno$id <= 400, ] kins <- example$GRM obj1 <- glmmkin(disease ~ age + sex, data = pheno, kins = kins, id = "id", family = binomial(link = "logit"), method = "REML", method.optim = "AI") select <- match(1:400, unique(obj1$id_include)) select[is.na(select)] <- 0 obj1.outfile.bed.noselect.1 <- tempfile() glmm.score(obj1, infile = plinkfiles, outfile = obj1.outfile.bed.noselect.1) obj1.bed.noselect.1 <- read.table(obj1.outfile.bed.noselect.1, header = TRUE, as.is = TRUE) obj1.outfile.bed.noselect.1.tmp <- tempfile() expect_error(glmm.score(obj1, infile = plinkfiles, outfile = obj1.outfile.bed.noselect.1.tmp, ncores = 2), "Error: parallel computing currently not implemented for PLINK binary format genotypes.") unlink(obj1.outfile.bed.noselect.1.tmp) obj1.outfile.bed.select.1 <- tempfile() glmm.score(obj1, infile = plinkfiles, select = select, outfile = obj1.outfile.bed.select.1) obj1.bed.select.1 <- read.table(obj1.outfile.bed.select.1, header = TRUE, as.is = TRUE) expect_equal(obj1.bed.noselect.1, obj1.bed.select.1) obj1.outfile.bgen.noselect.1 <- tempfile() glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, outfile = obj1.outfile.bgen.noselect.1) obj1.bgen.noselect.1 <- read.table(obj1.outfile.bgen.noselect.1, header = TRUE, as.is = TRUE) obj1.outfile.bgen.noselect.1.tmp <- tempfile() glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, outfile = obj1.outfile.bgen.noselect.1.tmp, ncores = 2) obj1.bgen.noselect.1.tmp <- read.table(obj1.outfile.bgen.noselect.1.tmp, header = TRUE, as.is = TRUE) expect_equal(obj1.bgen.noselect.1, obj1.bgen.noselect.1.tmp) unlink(obj1.outfile.bgen.noselect.1.tmp) obj1.outfile.bgen.select.1 <- tempfile() glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, select = select, outfile = obj1.outfile.bgen.select.1) obj1.bgen.select.1 <- read.table(obj1.outfile.bgen.select.1, header = TRUE, as.is = TRUE) expect_equal(obj1.bgen.noselect.1, obj1.bgen.select.1) expect_equal(obj1.bed.select.1[, c("SNP", "CHR", "POS", "A1", "A2", "N", "AF", "SCORE", "VAR", "PVAL")], obj1.bgen.select.1[, c("SNP", "CHR", "POS", "A1", "A2", "N", "AF", "SCORE", "VAR", "PVAL")]) if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", quietly = TRUE)) { obj1.outfile.gds.noselect.1 <- tempfile() glmm.score(obj1, infile = gdsfile, outfile = obj1.outfile.gds.noselect.1) obj1.gds.noselect.1 <- read.table(obj1.outfile.gds.noselect.1, header = TRUE, as.is = TRUE) obj1.outfile.gds.noselect.1.tmp <- tempfile() glmm.score(obj1, infile = gdsfile, outfile = obj1.outfile.gds.noselect.1.tmp, ncores = 2) obj1.gds.noselect.1.tmp <- read.table(obj1.outfile.gds.noselect.1.tmp, header = TRUE, as.is = TRUE) expect_equal(obj1.gds.noselect.1, obj1.gds.noselect.1.tmp) unlink(obj1.outfile.gds.noselect.1.tmp) obj1.outfile.gds.select.1 <- tempfile() Traceback: glmm.score(obj1, infile = gdsfile, select = select, outfile = obj1.outfile.gds.select.1) 1: obj1.gds.select.1 <- read.table(obj1.outfile.gds.select.1, eval(c.expr, envir = args, enclos = envir) header = TRUE, as.is = TRUE) expect_equal(obj1.gds.noselect.1, obj1.gds.select.1) 2: expect_equal(obj1.bed.select.1$PVAL, signif(obj1.gds.select.1$PVAL))eval(c.expr, envir = args, enclos = envir) expect_equal(signif(range(obj1.gds.select.1$PVAL)), signif(c(0.003804942, 0.986534857))) 3: unlink(c(obj1.outfile.gds.noselect.1, obj1.outfile.gds.select.1))doTryCatch(return(expr), name, parentenv, handler) } obj1.outfile.txt.select.1 <- tempfile() glmm.score(obj1, infile = txtfile, outfile = obj1.outfile.txt.select.1, 4: infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, tryCatchOne(expr, names, parentenv, handlers[[1L]]) select = select, infile.header.print = c("SNP", "Allele1", 5: "Allele2")) obj1.txt.select.1 <- read.table(obj1.outfile.txt.select.1, tryCatchList(expr, classes, parentenv, handlers) header = TRUE, as.is = TRUE) expect_equal(obj1.bed.select.1$PVAL, obj1.txt.select.1$PVAL) 6: tryCatch(eval(c.expr, envir = args, enclos = envir), error = function(e) e) obj1.outfile.txt.select.1.tmp <- tempfile() expect_error(glmm.score(obj1, infile = txtfile, outfile = obj1.outfile.txt.select.1.tmp, 7: FUN(X[[i]], ...) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", "Allele2"), ncores = 2), "Error: parallel computing currently not implemented for plain text format genotypes.") unlink(obj1.outfile.txt.select.1.tmp) 8: obj1.outfile.txt1.select.1 <- tempfile()lapply(X = S, FUN = FUN, ...) glmm.score(obj1, infile = txtfile1, outfile = obj1.outfile.txt1.select.1, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, 9: select = select, infile.header.print = c("SNP", "Allele1", doTryCatch(return(expr), name, parentenv, handler) "Allele2"))10: obj1.txt1.select.1 <- read.table(obj1.outfile.txt1.select.1, tryCatchOne(expr, names, parentenv, handlers[[1L]]) header = TRUE, as.is = TRUE) expect_equal(obj1.txt.select.1, obj1.txt1.select.1) obj1.outfile.txt2.select.1 <- tempfile() glmm.score(obj1, infile = txtfile2, outfile = obj1.outfile.txt2.select.1, 11: tryCatchList(expr, classes, parentenv, handlers) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, 12: select = select, infile.header.print = c("SNP", "Allele1", tryCatch(expr, error = function(e) { "Allele2")) call <- conditionCall(e) obj1.txt2.select.1 <- read.table(obj1.outfile.txt2.select.1, if (!is.null(call)) { header = TRUE, as.is = TRUE) if (identical(call[[1L]], quote(doTryCatch))) expect_equal(obj1.txt.select.1, obj1.txt2.select.1) call <- sys.call(-4L) dcall <- deparse(call, nlines = 1L) unlink(c(obj1.outfile.bed.noselect.1, obj1.outfile.bed.select.1, prefix <- paste("Error in", dcall, ": ") obj1.outfile.bgen.noselect.1, obj1.outfile.bgen.select.1, LONG <- 75L obj1.outfile.txt.select.1, obj1.outfile.txt1.select.1, sm <- strsplit(conditionMessage(e), "\n")[[1L]] obj1.outfile.txt2.select.1)) w <- 14L + nchar(dcall, type = "w") + nchar(sm[1L], type = "w") skip_on_cran() if (is.na(w)) obj2 <- glmmkin(disease ~ age + sex, data = pheno, kins = NULL, w <- 14L + nchar(dcall, type = "b") + nchar(sm[1L], type = "b") id = "id", family = binomial(link = "logit"), method = "REML", method.optim = "AI") if (w > LONG) select <- match(1:400, unique(obj2$id_include)) select[is.na(select)] <- 0 prefix <- paste0(prefix, "\n ") obj2.outfile.bed.noselect.1 <- tempfile() } glmm.score(obj2, infile = plinkfiles, outfile = obj2.outfile.bed.noselect.1) else prefix <- "Error : " obj2.bed.noselect.1 <- read.table(obj2.outfile.bed.noselect.1, msg <- paste0(prefix, conditionMessage(e), "\n") header = TRUE, as.is = TRUE) .Internal(seterrmessage(msg[1L])) if (!silent && isTRUE(getOption("show.error.messages"))) { obj2.outfile.bed.select.1 <- tempfile() glmm.score(obj2, infile = plinkfiles, select = select, outfile = obj2.outfile.bed.select.1) cat(msg, file = outFile) .Internal(printDeferredWarnings()) obj2.bed.select.1 <- read.table(obj2.outfile.bed.select.1, } header = TRUE, as.is = TRUE) invisible(structure(msg, class = "try-error", condition = e)) expect_equal(obj2.bed.noselect.1, obj2.bed.select.1)}) obj2.outfile.bgen.noselect.1 <- tempfile() glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, outfile = obj2.outfile.bgen.noselect.1)13: obj2.bgen.noselect.1 <- read.table(obj2.outfile.bgen.noselect.1, try(lapply(X = S, FUN = FUN, ...), silent = TRUE) header = TRUE, as.is = TRUE) obj2.outfile.bgen.select.1 <- tempfile()14: glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, sendMaster(try(lapply(X = S, FUN = FUN, ...), silent = TRUE)) select = select, outfile = obj2.outfile.bgen.select.1) obj2.bgen.select.1 <- read.table(obj2.outfile.bgen.select.1, header = TRUE, as.is = TRUE) expect_equal(obj2.bgen.noselect.1, obj2.bgen.select.1)15: expect_equal(obj2.bed.select.1[, c("SNP", "CHR", "POS", "A1", FUN(X[[i]], ...) "A2", "N", "AF", "SCORE", "VAR", "PVAL")], obj2.bgen.select.1[, 16: c("SNP", "CHR", "POS", "A1", "A2", "N", "AF", "SCORE", lapply(seq_len(cores), inner.do) "VAR", "PVAL")]) if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", 17: quietly = TRUE)) {mclapply(argsList, FUN, mc.preschedule = preschedule, mc.set.seed = set.seed, obj2.outfile.gds.noselect.1 <- tempfile() mc.silent = silent, mc.cores = cores) glmm.score(obj2, infile = gdsfile, outfile = obj2.outfile.gds.noselect.1)18: obj2.gds.noselect.1 <- read.table(obj2.outfile.gds.noselect.1, e$fun(obj, substitute(ex), parent.frame(), e$data) header = TRUE, as.is = TRUE) obj2.outfile.gds.select.1 <- tempfile() glmm.score(obj2, infile = gdsfile, select = select, outfile = obj2.outfile.gds.select.1)19: obj2.gds.select.1 <- read.table(obj2.outfile.gds.select.1, foreach(i = 1:ncores) %dopar% { header = TRUE, as.is = TRUE) expect_equal(obj2.gds.noselect.1, obj2.gds.select.1) if (!is.null(obj$P)) { if (bgenInfo$LayoutFlag == 2) { expect_equal(obj2.bed.select.1$PVAL, signif(obj2.gds.select.1$PVAL)) .Call(C_glmm_score_bgen13, as.numeric(res), obj$P, expect_equal(signif(range(obj2.gds.select.1$PVAL)), signif(c(0.003738918, 0.996996766))) infile, paste0(outfile, "_tmp.", i), center2, } MAF.range[1], MAF.range[2], miss.cutoff, miss.method, obj2.outfile.txt.select.1 <- tempfile() nperbatch, select, threadInfo$begin[i], threadInfo$end[i], glmm.score(obj2, infile = txtfile, outfile = obj2.outfile.txt.select.1, threadInfo$pos[i], bgenInfo$N, bgenInfo$CompressionFlag, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", 1) "Allele2")) } else { obj2.txt.select.1 <- read.table(obj2.outfile.txt.select.1, .Call(C_glmm_score_bgen11, as.numeric(res), obj$P, header = TRUE, as.is = TRUE) infile, paste0(outfile, "_tmp.", i), center2, MAF.range[1], MAF.range[2], miss.cutoff, miss.method, expect_equal(obj2.bed.select.1$PVAL, obj2.txt.select.1$PVAL) nperbatch, select, threadInfo$begin[i], threadInfo$end[i], obj2.outfile.txt1.select.1 <- tempfile() threadInfo$pos[i], bgenInfo$N, bgenInfo$CompressionFlag, glmm.score(obj2, infile = txtfile1, outfile = obj2.outfile.txt1.select.1, 1) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, } } select = select, infile.header.print = c("SNP", "Allele1", else { "Allele2")) if (bgenInfo$LayoutFlag == 2) { obj2.txt1.select.1 <- read.table(obj2.outfile.txt1.select.1, .Call(C_glmm_score_bgen13_sp, as.numeric(res), obj$Sigma_i, header = TRUE, as.is = TRUE) obj$Sigma_iX, obj$cov, infile, paste0(outfile, "_tmp.", i), center2, MAF.range[1], MAF.range[2], expect_equal(obj2.txt.select.1, obj2.txt1.select.1) miss.cutoff, miss.method, nperbatch, select, obj2.outfile.txt2.select.1 <- tempfile() threadInfo$begin[i], threadInfo$end[i], threadInfo$pos[i], glmm.score(obj2, infile = txtfile2, outfile = obj2.outfile.txt2.select.1, bgenInfo$N, bgenInfo$CompressionFlag, 1) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, } else { select = select, infile.header.print = c("SNP", "Allele1", .Call(C_glmm_score_bgen11_sp, as.numeric(res), obj$Sigma_i, "Allele2")) obj2.txt2.select.1 <- read.table(obj2.outfile.txt2.select.1, obj$Sigma_iX, obj$cov, infile, paste0(outfile, header = TRUE, as.is = TRUE) "_tmp.", i), center2, MAF.range[1], MAF.range[2], miss.cutoff, miss.method, nperbatch, select, expect_equal(obj2.txt.select.1, obj2.txt2.select.1) idx <- sample(nrow(pheno)) threadInfo$begin[i], threadInfo$end[i], threadInfo$pos[i], pheno <- pheno[idx, ] bgenInfo$N, bgenInfo$CompressionFlag, 1) obj1 <- glmmkin(disease ~ age + sex, data = pheno, kins = kins, } } id = "id", family = binomial(link = "logit"), method = "REML", } method.optim = "AI") select <- match(1:400, unique(obj1$id_include))20: glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, select[is.na(select)] <- 0 obj1.outfile.bed.noselect.2 <- tempfile() outfile = obj1.outfile.bgen.noselect.1.tmp, ncores = 2) glmm.score(obj1, infile = plinkfiles, outfile = obj1.outfile.bed.noselect.2) obj1.bed.noselect.2 <- read.table(obj1.outfile.bed.noselect.2, 21: header = TRUE, as.is = TRUE)eval(code, test_env) expect_equal(obj1.bed.noselect.1, obj1.bed.noselect.2) obj1.outfile.bed.select.2 <- tempfile() glmm.score(obj1, infile = plinkfiles, select = select, outfile = obj1.outfile.bed.select.2)22: eval(code, test_env) obj1.bed.select.2 <- read.table(obj1.outfile.bed.select.2, header = TRUE, as.is = TRUE) expect_equal(obj1.bed.select.1, obj1.bed.select.2) obj1.outfile.bgen.noselect.2 <- tempfile()23: withCallingHandlers({ glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, outfile = obj1.outfile.bgen.noselect.2) eval(code, test_env) obj1.bgen.noselect.2 <- read.table(obj1.outfile.bgen.noselect.2, new_expectations <- the$test_expectations > starting_expectations if (snapshot_skipped) { header = TRUE, as.is = TRUE) skip("On CRAN") expect_equal(obj1.bgen.noselect.1, obj1.bgen.noselect.2) obj1.outfile.bgen.select.2 <- tempfile() } glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, else if (!new_expectations && skip_on_empty) { select = select, outfile = obj1.outfile.bgen.select.2) skip_empty() obj1.bgen.select.2 <- read.table(obj1.outfile.bgen.select.2, } header = TRUE, as.is = TRUE)}, expectation = handle_expectation, packageNotFoundError = function(e) { expect_equal(obj1.bgen.select.1, obj1.bgen.select.2) if (on_cran()) { if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", skip(paste0("{", e$package, "} is not installed.")) quietly = TRUE)) { } obj1.outfile.gds.noselect.2 <- tempfile()}, snapshot_on_cran = function(cnd) { glmm.score(obj1, infile = gdsfile, outfile = obj1.outfile.gds.noselect.2) snapshot_skipped <<- TRUE obj1.gds.noselect.2 <- read.table(obj1.outfile.gds.noselect.2, header = TRUE, as.is = TRUE) invokeRestart("muffle_cran_snapshot") expect_equal(obj1.gds.noselect.1, obj1.gds.noselect.2)}, skip = handle_skip, warning = handle_warning, message = handle_message, obj1.outfile.gds.select.2 <- tempfile() error = handle_error, interrupt = handle_interrupt) glmm.score(obj1, infile = gdsfile, select = select, outfile = obj1.outfile.gds.select.2) obj1.gds.select.2 <- read.table(obj1.outfile.gds.select.2, 24: header = TRUE, as.is = TRUE) expect_equal(obj1.gds.select.1, obj1.gds.select.2)doTryCatch(return(expr), name, parentenv, handler) } obj1.outfile.txt.select.2 <- tempfile()25: glmm.score(obj1, infile = txtfile, outfile = obj1.outfile.txt.select.2, tryCatchOne(expr, names, parentenv, handlers[[1L]]) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", 26: tryCatchList(expr, classes, parentenv, handlers) "Allele2")) obj1.txt.select.2 <- read.table(obj1.outfile.txt.select.2, header = TRUE, as.is = TRUE)27: expect_equal(obj1.txt.select.1, obj1.txt.select.2) obj1.outfile.txt1.select.2 <- tempfile()tryCatch(withCallingHandlers({ glmm.score(obj1, infile = txtfile1, outfile = obj1.outfile.txt1.select.2, eval(code, test_env) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", new_expectations <- the$test_expectations > starting_expectations "Allele2")) if (snapshot_skipped) { obj1.txt1.select.2 <- read.table(obj1.outfile.txt1.select.2, skip("On CRAN") header = TRUE, as.is = TRUE) } expect_equal(obj1.txt1.select.1, obj1.txt1.select.2) else if (!new_expectations && skip_on_empty) { obj1.outfile.txt2.select.2 <- tempfile() glmm.score(obj1, infile = txtfile2, outfile = obj1.outfile.txt2.select.2, skip_empty() infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, } select = select, infile.header.print = c("SNP", "Allele1", "Allele2"))}, expectation = handle_expectation, packageNotFoundError = function(e) { if (on_cran()) { obj1.txt2.select.2 <- read.table(obj1.outfile.txt2.select.2, header = TRUE, as.is = TRUE) skip(paste0("{", e$package, "} is not installed.")) expect_equal(obj1.txt2.select.1, obj1.txt2.select.2) } obj2 <- glmmkin(disease ~ age + sex, data = pheno, kins = NULL, }, snapshot_on_cran = function(cnd) { id = "id", family = binomial(link = "logit"), method = "REML", method.optim = "AI") select <- match(1:400, unique(obj2$id_include)) snapshot_skipped <<- TRUE select[is.na(select)] <- 0 invokeRestart("muffle_cran_snapshot") obj2.outfile.bed.noselect.2 <- tempfile()}, skip = handle_skip, warning = handle_warning, message = handle_message, glmm.score(obj2, infile = plinkfiles, outfile = obj2.outfile.bed.noselect.2) error = handle_error, interrupt = handle_interrupt), error = handle_fatal) obj2.bed.noselect.2 <- read.table(obj2.outfile.bed.noselect.2, 28: doWithOneRestart(return(expr), restart) header = TRUE, as.is = TRUE) expect_equal(obj2.bed.noselect.1, obj2.bed.noselect.2)29: obj2.outfile.bed.select.2 <- tempfile() glmm.score(obj2, infile = plinkfiles, select = select, outfile = obj2.outfile.bed.select.2)withOneRestart(expr, restarts[[1L]]) obj2.bed.select.2 <- read.table(obj2.outfile.bed.select.2, header = TRUE, as.is = TRUE)30: expect_equal(obj2.bed.select.1, obj2.bed.select.2)withRestarts(tryCatch(withCallingHandlers({ obj2.outfile.bgen.noselect.2 <- tempfile() eval(code, test_env) glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, new_expectations <- the$test_expectations > starting_expectations outfile = obj2.outfile.bgen.noselect.2) if (snapshot_skipped) { obj2.bgen.noselect.2 <- read.table(obj2.outfile.bgen.noselect.2, skip("On CRAN") header = TRUE, as.is = TRUE) } expect_equal(obj2.bgen.noselect.1, obj2.bgen.noselect.2) else if (!new_expectations && skip_on_empty) { obj2.outfile.bgen.select.2 <- tempfile() skip_empty() glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, } select = select, outfile = obj2.outfile.bgen.select.2)}, expectation = handle_expectation, packageNotFoundError = function(e) { obj2.bgen.select.2 <- read.table(obj2.outfile.bgen.select.2, if (on_cran()) { header = TRUE, as.is = TRUE) skip(paste0("{", e$package, "} is not installed.")) } expect_equal(obj2.bgen.select.1, obj2.bgen.select.2)}, snapshot_on_cran = function(cnd) { if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", snapshot_skipped <<- TRUE quietly = TRUE)) { invokeRestart("muffle_cran_snapshot") obj2.outfile.gds.noselect.2 <- tempfile()}, skip = handle_skip, warning = handle_warning, message = handle_message, glmm.score(obj2, infile = gdsfile, outfile = obj2.outfile.gds.noselect.2) error = handle_error, interrupt = handle_interrupt), error = handle_fatal), obj2.gds.noselect.2 <- read.table(obj2.outfile.gds.noselect.2, end_test = function() { header = TRUE, as.is = TRUE) }) expect_equal(obj2.gds.noselect.1, obj2.gds.noselect.2) obj2.outfile.gds.select.2 <- tempfile()31: glmm.score(obj2, infile = gdsfile, select = select, outfile = obj2.outfile.gds.select.2)test_code(code, parent.frame()) obj2.gds.select.2 <- read.table(obj2.outfile.gds.select.2, header = TRUE, as.is = TRUE)32: expect_equal(obj2.gds.select.1, obj2.gds.select.2)test_that("cross-sectional id le 400 binomial", { } plinkfiles <- strsplit(system.file("extdata", "geno.bed", obj2.outfile.txt.select.2 <- tempfile() package = "GMMAT"), ".bed", fixed = TRUE)[[1]] glmm.score(obj2, infile = txtfile, outfile = obj2.outfile.txt.select.2, bgenfile <- system.file("extdata", "geno.bgen", package = "GMMAT") infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, samplefile <- system.file("extdata", "geno.sample", package = "GMMAT") select = select, infile.header.print = c("SNP", "Allele1", gdsfile <- system.file("extdata", "geno.gds", package = "GMMAT") "Allele2")) txtfile <- system.file("extdata", "geno.txt", package = "GMMAT") obj2.txt.select.2 <- read.table(obj2.outfile.txt.select.2, txtfile1 <- system.file("extdata", "geno.txt.gz", package = "GMMAT") header = TRUE, as.is = TRUE) txtfile2 <- system.file("extdata", "geno.txt.bz2", package = "GMMAT") expect_equal(obj2.txt.select.1, obj2.txt.select.2) data(example) obj2.outfile.txt1.select.2 <- tempfile() suppressWarnings(RNGversion("3.5.0")) glmm.score(obj2, infile = txtfile1, outfile = obj2.outfile.txt1.select.2, set.seed(123) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, pheno <- rbind(example$pheno, example$pheno[1:100, ]) select = select, infile.header.print = c("SNP", "Allele1", pheno$id <- 1:500 "Allele2")) pheno$disease[sample(1:500, 20)] <- NA obj2.txt1.select.2 <- read.table(obj2.outfile.txt1.select.2, pheno$age[sample(1:500, 20)] <- NA header = TRUE, as.is = TRUE) pheno$sex[sample(1:500, 20)] <- NA expect_equal(obj2.txt1.select.1, obj2.txt1.select.2) pheno <- pheno[sample(1:500, 450), ] obj2.outfile.txt2.select.2 <- tempfile() pheno <- pheno[pheno$id <= 400, ] glmm.score(obj2, infile = txtfile2, outfile = obj2.outfile.txt2.select.2, kins <- example$GRM infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, obj1 <- glmmkin(disease ~ age + sex, data = pheno, kins = kins, select = select, infile.header.print = c("SNP", "Allele1", id = "id", family = binomial(link = "logit"), method = "REML", "Allele2")) method.optim = "AI") obj2.txt2.select.2 <- read.table(obj2.outfile.txt2.select.2, select <- match(1:400, unique(obj1$id_include)) header = TRUE, as.is = TRUE) select[is.na(select)] <- 0 expect_equal(obj2.txt2.select.1, obj2.txt2.select.2) obj1.outfile.bed.noselect.1 <- tempfile() idx <- sample(nrow(kins)) glmm.score(obj1, infile = plinkfiles, outfile = obj1.outfile.bed.noselect.1) kins <- kins[idx, idx] obj1.bed.noselect.1 <- read.table(obj1.outfile.bed.noselect.1, obj1 <- glmmkin(disease ~ age + sex, data = pheno, kins = kins, header = TRUE, as.is = TRUE) id = "id", family = binomial(link = "logit"), method = "REML", obj1.outfile.bed.noselect.1.tmp <- tempfile() method.optim = "AI") expect_error(glmm.score(obj1, infile = plinkfiles, outfile = obj1.outfile.bed.noselect.1.tmp, select <- match(1:400, unique(obj1$id_include)) ncores = 2), "Error: parallel computing currently not implemented for PLINK binary format genotypes.") select[is.na(select)] <- 0 unlink(obj1.outfile.bed.noselect.1.tmp) obj1.outfile.bed.noselect.3 <- tempfile() obj1.outfile.bed.select.1 <- tempfile() glmm.score(obj1, infile = plinkfiles, outfile = obj1.outfile.bed.noselect.3) glmm.score(obj1, infile = plinkfiles, select = select, outfile = obj1.outfile.bed.select.1) obj1.bed.noselect.3 <- read.table(obj1.outfile.bed.noselect.3, obj1.bed.select.1 <- read.table(obj1.outfile.bed.select.1, header = TRUE, as.is = TRUE) header = TRUE, as.is = TRUE) expect_equal(obj1.bed.noselect.1, obj1.bed.noselect.3) expect_equal(obj1.bed.noselect.1, obj1.bed.select.1) obj1.outfile.bed.select.3 <- tempfile() obj1.outfile.bgen.noselect.1 <- tempfile() glmm.score(obj1, infile = plinkfiles, select = select, outfile = obj1.outfile.bed.select.3) glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, obj1.bed.select.3 <- read.table(obj1.outfile.bed.select.3, outfile = obj1.outfile.bgen.noselect.1) header = TRUE, as.is = TRUE) obj1.bgen.noselect.1 <- read.table(obj1.outfile.bgen.noselect.1, expect_equal(obj1.bed.select.1, obj1.bed.select.3) header = TRUE, as.is = TRUE) obj1.outfile.bgen.noselect.3 <- tempfile() obj1.outfile.bgen.noselect.1.tmp <- tempfile() glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, outfile = obj1.outfile.bgen.noselect.3) outfile = obj1.outfile.bgen.noselect.1.tmp, ncores = 2) obj1.bgen.noselect.3 <- read.table(obj1.outfile.bgen.noselect.3, obj1.bgen.noselect.1.tmp <- read.table(obj1.outfile.bgen.noselect.1.tmp, header = TRUE, as.is = TRUE) header = TRUE, as.is = TRUE) expect_equal(obj1.bgen.noselect.1, obj1.bgen.noselect.3) expect_equal(obj1.bgen.noselect.1, obj1.bgen.noselect.1.tmp) obj1.outfile.bgen.select.3 <- tempfile() unlink(obj1.outfile.bgen.noselect.1.tmp) glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, obj1.outfile.bgen.select.1 <- tempfile() select = select, outfile = obj1.outfile.bgen.select.3) glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, obj1.bgen.select.3 <- read.table(obj1.outfile.bgen.select.3, select = select, outfile = obj1.outfile.bgen.select.1) header = TRUE, as.is = TRUE) obj1.bgen.select.1 <- read.table(obj1.outfile.bgen.select.1, expect_equal(obj1.bgen.select.1, obj1.bgen.select.3) header = TRUE, as.is = TRUE) if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", expect_equal(obj1.bgen.noselect.1, obj1.bgen.select.1) quietly = TRUE)) { expect_equal(obj1.bed.select.1[, c("SNP", "CHR", "POS", "A1", obj1.outfile.gds.noselect.3 <- tempfile() "A2", "N", "AF", "SCORE", "VAR", "PVAL")], obj1.bgen.select.1[, glmm.score(obj1, infile = gdsfile, outfile = obj1.outfile.gds.noselect.3) c("SNP", "CHR", "POS", "A1", "A2", "N", "AF", "SCORE", obj1.gds.noselect.3 <- read.table(obj1.outfile.gds.noselect.3, "VAR", "PVAL")]) header = TRUE, as.is = TRUE) if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", expect_equal(obj1.gds.noselect.1, obj1.gds.noselect.3) quietly = TRUE)) { obj1.outfile.gds.select.3 <- tempfile() obj1.outfile.gds.noselect.1 <- tempfile() glmm.score(obj1, infile = gdsfile, select = select, outfile = obj1.outfile.gds.select.3) glmm.score(obj1, infile = gdsfile, outfile = obj1.outfile.gds.noselect.1) obj1.gds.select.3 <- read.table(obj1.outfile.gds.select.3, obj1.gds.noselect.1 <- read.table(obj1.outfile.gds.noselect.1, header = TRUE, as.is = TRUE) header = TRUE, as.is = TRUE) expect_equal(obj1.gds.select.1, obj1.gds.select.3) obj1.outfile.gds.noselect.1.tmp <- tempfile() } glmm.score(obj1, infile = gdsfile, outfile = obj1.outfile.gds.noselect.1.tmp, obj1.outfile.txt.select.3 <- tempfile() ncores = 2) glmm.score(obj1, infile = txtfile, outfile = obj1.outfile.txt.select.3, obj1.gds.noselect.1.tmp <- read.table(obj1.outfile.gds.noselect.1.tmp, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, header = TRUE, as.is = TRUE) select = select, infile.header.print = c("SNP", "Allele1", expect_equal(obj1.gds.noselect.1, obj1.gds.noselect.1.tmp) "Allele2")) unlink(obj1.outfile.gds.noselect.1.tmp) obj1.txt.select.3 <- read.table(obj1.outfile.txt.select.3, obj1.outfile.gds.select.1 <- tempfile() header = TRUE, as.is = TRUE) glmm.score(obj1, infile = gdsfile, select = select, outfile = obj1.outfile.gds.select.1) expect_equal(obj1.txt.select.1, obj1.txt.select.3) obj1.gds.select.1 <- read.table(obj1.outfile.gds.select.1, obj1.outfile.txt1.select.3 <- tempfile() header = TRUE, as.is = TRUE) glmm.score(obj1, infile = txtfile1, outfile = obj1.outfile.txt1.select.3, expect_equal(obj1.gds.noselect.1, obj1.gds.select.1) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, expect_equal(obj1.bed.select.1$PVAL, signif(obj1.gds.select.1$PVAL)) select = select, infile.header.print = c("SNP", "Allele1", expect_equal(signif(range(obj1.gds.select.1$PVAL)), signif(c(0.003804942, "Allele2")) 0.986534857))) obj1.txt1.select.3 <- read.table(obj1.outfile.txt1.select.3, unlink(c(obj1.outfile.gds.noselect.1, obj1.outfile.gds.select.1)) header = TRUE, as.is = TRUE) } expect_equal(obj1.txt1.select.1, obj1.txt1.select.3) obj1.outfile.txt.select.1 <- tempfile() obj1.outfile.txt2.select.3 <- tempfile() glmm.score(obj1, infile = txtfile, outfile = obj1.outfile.txt.select.1, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, glmm.score(obj1, infile = txtfile2, outfile = obj1.outfile.txt2.select.3, select = select, infile.header.print = c("SNP", "Allele1", "Allele2")) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, obj1.txt.select.1 <- read.table(obj1.outfile.txt.select.1, select = select, infile.header.print = c("SNP", "Allele1", header = TRUE, as.is = TRUE) "Allele2")) expect_equal(obj1.bed.select.1$PVAL, obj1.txt.select.1$PVAL) obj1.txt2.select.3 <- read.table(obj1.outfile.txt2.select.3, obj1.outfile.txt.select.1.tmp <- tempfile() header = TRUE, as.is = TRUE) expect_error(glmm.score(obj1, infile = txtfile, outfile = obj1.outfile.txt.select.1.tmp, expect_equal(obj1.txt2.select.1, obj1.txt2.select.3) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, obj2 <- glmmkin(disease ~ age + sex, data = pheno, kins = NULL, select = select, infile.header.print = c("SNP", "Allele1", id = "id", family = binomial(link = "logit"), method = "REML", "Allele2"), ncores = 2), "Error: parallel computing currently not implemented for plain text format genotypes.") method.optim = "AI") unlink(obj1.outfile.txt.select.1.tmp) select <- match(1:400, unique(obj2$id_include)) obj1.outfile.txt1.select.1 <- tempfile() select[is.na(select)] <- 0 glmm.score(obj1, infile = txtfile1, outfile = obj1.outfile.txt1.select.1, obj2.outfile.bed.noselect.3 <- tempfile() infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, glmm.score(obj2, infile = plinkfiles, outfile = obj2.outfile.bed.noselect.3) select = select, infile.header.print = c("SNP", "Allele1", obj2.bed.noselect.3 <- read.table(obj2.outfile.bed.noselect.3, "Allele2")) header = TRUE, as.is = TRUE) obj1.txt1.select.1 <- read.table(obj1.outfile.txt1.select.1, expect_equal(obj2.bed.noselect.1, obj2.bed.noselect.3) obj2.outfile.bed.select.3 <- tempfile() header = TRUE, as.is = TRUE) glmm.score(obj2, infile = plinkfiles, select = select, outfile = obj2.outfile.bed.select.3) expect_equal(obj1.txt.select.1, obj1.txt1.select.1) obj2.bed.select.3 <- read.table(obj2.outfile.bed.select.3, obj1.outfile.txt2.select.1 <- tempfile() header = TRUE, as.is = TRUE) glmm.score(obj1, infile = txtfile2, outfile = obj1.outfile.txt2.select.1, expect_equal(obj2.bed.select.1, obj2.bed.select.3) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", obj2.outfile.bgen.noselect.3 <- tempfile() "Allele2")) glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, obj1.txt2.select.1 <- read.table(obj1.outfile.txt2.select.1, outfile = obj2.outfile.bgen.noselect.3) header = TRUE, as.is = TRUE) obj2.bgen.noselect.3 <- read.table(obj2.outfile.bgen.noselect.3, expect_equal(obj1.txt.select.1, obj1.txt2.select.1) header = TRUE, as.is = TRUE) unlink(c(obj1.outfile.bed.noselect.1, obj1.outfile.bed.select.1, expect_equal(obj2.bgen.noselect.1, obj2.bgen.noselect.3) obj1.outfile.bgen.noselect.1, obj1.outfile.bgen.select.1, obj2.outfile.bgen.select.3 <- tempfile() obj1.outfile.txt.select.1, obj1.outfile.txt1.select.1, glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, obj1.outfile.txt2.select.1)) select = select, outfile = obj2.outfile.bgen.select.3) skip_on_cran() obj2.bgen.select.3 <- read.table(obj2.outfile.bgen.select.3, obj2 <- glmmkin(disease ~ age + sex, data = pheno, kins = NULL, header = TRUE, as.is = TRUE) id = "id", family = binomial(link = "logit"), method = "REML", expect_equal(obj2.bgen.select.1, obj2.bgen.select.3) method.optim = "AI") if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", select <- match(1:400, unique(obj2$id_include)) select[is.na(select)] <- 0 quietly = TRUE)) { obj2.outfile.bed.noselect.1 <- tempfile() obj2.outfile.gds.noselect.3 <- tempfile() glmm.score(obj2, infile = plinkfiles, outfile = obj2.outfile.bed.noselect.1) glmm.score(obj2, infile = gdsfile, outfile = obj2.outfile.gds.noselect.3) obj2.bed.noselect.1 <- read.table(obj2.outfile.bed.noselect.1, obj2.gds.noselect.3 <- read.table(obj2.outfile.gds.noselect.3, header = TRUE, as.is = TRUE) header = TRUE, as.is = TRUE) obj2.outfile.bed.select.1 <- tempfile() expect_equal(obj2.gds.noselect.1, obj2.gds.noselect.3) glmm.score(obj2, infile = plinkfiles, select = select, outfile = obj2.outfile.bed.select.1) obj2.outfile.gds.select.3 <- tempfile() obj2.bed.select.1 <- read.table(obj2.outfile.bed.select.1, glmm.score(obj2, infile = gdsfile, select = select, outfile = obj2.outfile.gds.select.3) header = TRUE, as.is = TRUE) obj2.gds.select.3 <- read.table(obj2.outfile.gds.select.3, expect_equal(obj2.bed.noselect.1, obj2.bed.select.1) header = TRUE, as.is = TRUE) obj2.outfile.bgen.noselect.1 <- tempfile() expect_equal(obj2.gds.select.1, obj2.gds.select.3) glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, } outfile = obj2.outfile.bgen.noselect.1) obj2.outfile.txt.select.3 <- tempfile() obj2.bgen.noselect.1 <- read.table(obj2.outfile.bgen.noselect.1, glmm.score(obj2, infile = txtfile, outfile = obj2.outfile.txt.select.3, header = TRUE, as.is = TRUE) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, obj2.outfile.bgen.select.1 <- tempfile() select = select, infile.header.print = c("SNP", "Allele1", glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, "Allele2")) select = select, outfile = obj2.outfile.bgen.select.1) obj2.txt.select.3 <- read.table(obj2.outfile.txt.select.3, obj2.bgen.select.1 <- read.table(obj2.outfile.bgen.select.1, header = TRUE, as.is = TRUE) expect_equal(obj2.txt.select.1, obj2.txt.select.3) header = TRUE, as.is = TRUE) obj2.outfile.txt1.select.3 <- tempfile() expect_equal(obj2.bgen.noselect.1, obj2.bgen.select.1) glmm.score(obj2, infile = txtfile1, outfile = obj2.outfile.txt1.select.3, expect_equal(obj2.bed.select.1[, c("SNP", "CHR", "POS", "A1", infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, "A2", "N", "AF", "SCORE", "VAR", "PVAL")], obj2.bgen.select.1[, select = select, infile.header.print = c("SNP", "Allele1", c("SNP", "CHR", "POS", "A1", "A2", "N", "AF", "SCORE", "Allele2")) "VAR", "PVAL")]) obj2.txt1.select.3 <- read.table(obj2.outfile.txt1.select.3, if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", header = TRUE, as.is = TRUE) quietly = TRUE)) { expect_equal(obj2.txt1.select.1, obj2.txt1.select.3) obj2.outfile.gds.noselect.1 <- tempfile() obj2.outfile.txt2.select.3 <- tempfile() glmm.score(obj2, infile = gdsfile, outfile = obj2.outfile.gds.noselect.1) glmm.score(obj2, infile = txtfile2, outfile = obj2.outfile.txt2.select.3, obj2.gds.noselect.1 <- read.table(obj2.outfile.gds.noselect.1, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, header = TRUE, as.is = TRUE) select = select, infile.header.print = c("SNP", "Allele1", obj2.outfile.gds.select.1 <- tempfile() "Allele2")) glmm.score(obj2, infile = gdsfile, select = select, outfile = obj2.outfile.gds.select.1) obj2.txt2.select.3 <- read.table(obj2.outfile.txt2.select.3, obj2.gds.select.1 <- read.table(obj2.outfile.gds.select.1, header = TRUE, as.is = TRUE) header = TRUE, as.is = TRUE) expect_equal(obj2.txt2.select.1, obj2.txt2.select.3) expect_equal(obj2.gds.noselect.1, obj2.gds.select.1) unlink(c(obj2.outfile.bed.noselect.1, obj2.outfile.bed.select.1, expect_equal(obj2.bed.select.1$PVAL, signif(obj2.gds.select.1$PVAL)) obj2.outfile.bgen.noselect.1, obj2.outfile.bgen.select.1, expect_equal(signif(range(obj2.gds.select.1$PVAL)), signif(c(0.003738918, obj2.outfile.txt.select.1, obj2.outfile.txt1.select.1, 0.996996766))) } obj2.outfile.txt2.select.1)) obj2.outfile.txt.select.1 <- tempfile() unlink(c(obj1.outfile.bed.noselect.2, obj1.outfile.bed.select.2, glmm.score(obj2, infile = txtfile, outfile = obj2.outfile.txt.select.1, obj1.outfile.bgen.noselect.2, obj1.outfile.bgen.select.2, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, obj1.outfile.txt.select.2, obj1.outfile.txt1.select.2, select = select, infile.header.print = c("SNP", "Allele1", obj1.outfile.txt2.select.2)) "Allele2")) unlink(c(obj2.outfile.bed.noselect.2, obj2.outfile.bed.select.2, obj2.txt.select.1 <- read.table(obj2.outfile.txt.select.1, obj2.outfile.bgen.noselect.2, obj2.outfile.bgen.select.2, header = TRUE, as.is = TRUE) obj2.outfile.txt.select.2, obj2.outfile.txt1.select.2, expect_equal(obj2.bed.select.1$PVAL, obj2.txt.select.1$PVAL) obj2.outfile.txt2.select.2)) obj2.outfile.txt1.select.1 <- tempfile() unlink(c(obj1.outfile.bed.noselect.3, obj1.outfile.bed.select.3, glmm.score(obj2, infile = txtfile1, outfile = obj2.outfile.txt1.select.1, obj1.outfile.bgen.noselect.3, obj1.outfile.bgen.select.3, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, obj1.outfile.txt.select.3, obj1.outfile.txt1.select.3, select = select, infile.header.print = c("SNP", "Allele1", obj1.outfile.txt2.select.3)) "Allele2")) unlink(c(obj2.outfile.bed.noselect.3, obj2.outfile.bed.select.3, obj2.txt1.select.1 <- read.table(obj2.outfile.txt1.select.1, header = TRUE, as.is = TRUE) obj2.outfile.bgen.noselect.3, obj2.outfile.bgen.select.3, expect_equal(obj2.txt.select.1, obj2.txt1.select.1) obj2.outfile.txt.select.3, obj2.outfile.txt1.select.3, obj2.outfile.txt2.select.1 <- tempfile() obj2.outfile.txt2.select.3)) glmm.score(obj2, infile = txtfile2, outfile = obj2.outfile.txt2.select.1, if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, quietly = TRUE)) select = select, infile.header.print = c("SNP", "Allele1", unlink(c(obj2.outfile.gds.noselect.1, obj2.outfile.gds.select.1, "Allele2")) obj1.outfile.gds.noselect.2, obj1.outfile.gds.select.2, obj2.txt2.select.1 <- read.table(obj2.outfile.txt2.select.1, obj2.outfile.gds.noselect.2, obj2.outfile.gds.select.2, header = TRUE, as.is = TRUE) obj1.outfile.gds.noselect.3, obj1.outfile.gds.select.3, expect_equal(obj2.txt.select.1, obj2.txt2.select.1) obj2.outfile.gds.noselect.3, obj2.outfile.gds.select.3)) idx <- sample(nrow(pheno))}) pheno <- pheno[idx, ] obj1 <- glmmkin(disease ~ age + sex, data = pheno, kins = kins, 33: id = "id", family = binomial(link = "logit"), method = "REML", eval(code, test_env) method.optim = "AI") select <- match(1:400, unique(obj1$id_include))34: select[is.na(select)] <- 0eval(code, test_env) obj1.outfile.bed.noselect.2 <- tempfile() glmm.score(obj1, infile = plinkfiles, outfile = obj1.outfile.bed.noselect.2) obj1.bed.noselect.2 <- read.table(obj1.outfile.bed.noselect.2, 35: header = TRUE, as.is = TRUE)withCallingHandlers({ expect_equal(obj1.bed.noselect.1, obj1.bed.noselect.2) eval(code, test_env) obj1.outfile.bed.select.2 <- tempfile() new_expectations <- the$test_expectations > starting_expectations glmm.score(obj1, infile = plinkfiles, select = select, outfile = obj1.outfile.bed.select.2) if (snapshot_skipped) { obj1.bed.select.2 <- read.table(obj1.outfile.bed.select.2, skip("On CRAN") header = TRUE, as.is = TRUE) } expect_equal(obj1.bed.select.1, obj1.bed.select.2) else if (!new_expectations && skip_on_empty) { obj1.outfile.bgen.noselect.2 <- tempfile() skip_empty() glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, } outfile = obj1.outfile.bgen.noselect.2)}, expectation = handle_expectation, packageNotFoundError = function(e) { obj1.bgen.noselect.2 <- read.table(obj1.outfile.bgen.noselect.2, if (on_cran()) { header = TRUE, as.is = TRUE) skip(paste0("{", e$package, "} is not installed.")) expect_equal(obj1.bgen.noselect.1, obj1.bgen.noselect.2) } obj1.outfile.bgen.select.2 <- tempfile()}, snapshot_on_cran = function(cnd) { glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, snapshot_skipped <<- TRUE select = select, outfile = obj1.outfile.bgen.select.2) invokeRestart("muffle_cran_snapshot") obj1.bgen.select.2 <- read.table(obj1.outfile.bgen.select.2, }, skip = handle_skip, warning = handle_warning, message = handle_message, header = TRUE, as.is = TRUE) error = handle_error, interrupt = handle_interrupt) expect_equal(obj1.bgen.select.1, obj1.bgen.select.2) if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", 36: quietly = TRUE)) {doTryCatch(return(expr), name, parentenv, handler) obj1.outfile.gds.noselect.2 <- tempfile() glmm.score(obj1, infile = gdsfile, outfile = obj1.outfile.gds.noselect.2)37: obj1.gds.noselect.2 <- read.table(obj1.outfile.gds.noselect.2, tryCatchOne(expr, names, parentenv, handlers[[1L]]) header = TRUE, as.is = TRUE) expect_equal(obj1.gds.noselect.1, obj1.gds.noselect.2)38: obj1.outfile.gds.select.2 <- tempfile()tryCatchList(expr, classes, parentenv, handlers) glmm.score(obj1, infile = gdsfile, select = select, outfile = obj1.outfile.gds.select.2) obj1.gds.select.2 <- read.table(obj1.outfile.gds.select.2, 39: header = TRUE, as.is = TRUE)tryCatch(withCallingHandlers({ expect_equal(obj1.gds.select.1, obj1.gds.select.2) eval(code, test_env) } new_expectations <- the$test_expectations > starting_expectations obj1.outfile.txt.select.2 <- tempfile() if (snapshot_skipped) { glmm.score(obj1, infile = txtfile, outfile = obj1.outfile.txt.select.2, skip("On CRAN") infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, } select = select, infile.header.print = c("SNP", "Allele1", else if (!new_expectations && skip_on_empty) { "Allele2")) skip_empty() obj1.txt.select.2 <- read.table(obj1.outfile.txt.select.2, } header = TRUE, as.is = TRUE)}, expectation = handle_expectation, packageNotFoundError = function(e) { expect_equal(obj1.txt.select.1, obj1.txt.select.2) if (on_cran()) { obj1.outfile.txt1.select.2 <- tempfile() skip(paste0("{", e$package, "} is not installed.")) glmm.score(obj1, infile = txtfile1, outfile = obj1.outfile.txt1.select.2, } infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, }, snapshot_on_cran = function(cnd) { select = select, infile.header.print = c("SNP", "Allele1", snapshot_skipped <<- TRUE "Allele2")) invokeRestart("muffle_cran_snapshot") obj1.txt1.select.2 <- read.table(obj1.outfile.txt1.select.2, }, skip = handle_skip, warning = handle_warning, message = handle_message, header = TRUE, as.is = TRUE) error = handle_error, interrupt = handle_interrupt), error = handle_fatal) expect_equal(obj1.txt1.select.1, obj1.txt1.select.2) obj1.outfile.txt2.select.2 <- tempfile()40: glmm.score(obj1, infile = txtfile2, outfile = obj1.outfile.txt2.select.2, doWithOneRestart(return(expr), restart) infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", "Allele2")) obj1.txt2.select.2 <- read.table(obj1.outfile.txt2.select.2, 41: header = TRUE, as.is = TRUE)withOneRestart(expr, restarts[[1L]]) expect_equal(obj1.txt2.select.1, obj1.txt2.select.2) 42: obj2 <- glmmkin(disease ~ age + sex, data = pheno, kins = NULL, withRestarts(tryCatch(withCallingHandlers({ id = "id", family = binomial(link = "logit"), method = "REML", eval(code, test_env) method.optim = "AI") new_expectations <- the$test_expectations > starting_expectations select <- match(1:400, unique(obj2$id_include)) if (snapshot_skipped) { skip("On CRAN") select[is.na(select)] <- 0 obj2.outfile.bed.noselect.2 <- tempfile() } glmm.score(obj2, infile = plinkfiles, outfile = obj2.outfile.bed.noselect.2) else if (!new_expectations && skip_on_empty) { obj2.bed.noselect.2 <- read.table(obj2.outfile.bed.noselect.2, skip_empty() header = TRUE, as.is = TRUE) expect_equal(obj2.bed.noselect.1, obj2.bed.noselect.2) } obj2.outfile.bed.select.2 <- tempfile()}, expectation = handle_expectation, packageNotFoundError = function(e) { if (on_cran()) { glmm.score(obj2, infile = plinkfiles, select = select, outfile = obj2.outfile.bed.select.2) obj2.bed.select.2 <- read.table(obj2.outfile.bed.select.2, skip(paste0("{", e$package, "} is not installed.")) header = TRUE, as.is = TRUE) } expect_equal(obj2.bed.select.1, obj2.bed.select.2)}, snapshot_on_cran = function(cnd) { obj2.outfile.bgen.noselect.2 <- tempfile() snapshot_skipped <<- TRUE glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, invokeRestart("muffle_cran_snapshot") outfile = obj2.outfile.bgen.noselect.2)}, skip = handle_skip, warning = handle_warning, message = handle_message, obj2.bgen.noselect.2 <- read.table(obj2.outfile.bgen.noselect.2, error = handle_error, interrupt = handle_interrupt), error = handle_fatal), header = TRUE, as.is = TRUE) end_test = function() { expect_equal(obj2.bgen.noselect.1, obj2.bgen.noselect.2) }) obj2.outfile.bgen.select.2 <- tempfile() glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, 43: select = select, outfile = obj2.outfile.bgen.select.2)test_code(code = exprs, env = env, reporter = get_reporter() %||% obj2.bgen.select.2 <- read.table(obj2.outfile.bgen.select.2, StopReporter$new()) header = TRUE, as.is = TRUE) expect_equal(obj2.bgen.select.1, obj2.bgen.select.2) if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", 44: quietly = TRUE)) {source_file(path, env = env(env), desc = desc, shuffle = shuffle, obj2.outfile.gds.noselect.2 <- tempfile() error_call = error_call) glmm.score(obj2, infile = gdsfile, outfile = obj2.outfile.gds.noselect.2) 45: obj2.gds.noselect.2 <- read.table(obj2.outfile.gds.noselect.2, FUN(X[[i]], ...) header = TRUE, as.is = TRUE) expect_equal(obj2.gds.noselect.1, obj2.gds.noselect.2)46: obj2.outfile.gds.select.2 <- tempfile() glmm.score(obj2, infile = gdsfile, select = select, outfile = obj2.outfile.gds.select.2)lapply(test_paths, test_one_file, env = env, desc = desc, shuffle = shuffle, error_call = error_call) obj2.gds.select.2 <- read.table(obj2.outfile.gds.select.2, header = TRUE, as.is = TRUE) expect_equal(obj2.gds.select.1, obj2.gds.select.2)47: }doTryCatch(return(expr), name, parentenv, handler) obj2.outfile.txt.select.2 <- tempfile() glmm.score(obj2, infile = txtfile, outfile = obj2.outfile.txt.select.2, 48: infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", tryCatchOne(expr, names, parentenv, handlers[[1L]]) "Allele2")) obj2.txt.select.2 <- read.table(obj2.outfile.txt.select.2, 49: tryCatchList(expr, classes, parentenv, handlers) header = TRUE, as.is = TRUE) expect_equal(obj2.txt.select.1, obj2.txt.select.2) obj2.outfile.txt1.select.2 <- tempfile()50: glmm.score(obj2, infile = txtfile1, outfile = obj2.outfile.txt1.select.2, tryCatch(code, testthat_abort_reporter = function(cnd) { infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, cat(conditionMessage(cnd), "\n") select = select, infile.header.print = c("SNP", "Allele1", NULL}) "Allele2")) obj2.txt1.select.2 <- read.table(obj2.outfile.txt1.select.2, header = TRUE, as.is = TRUE)51: with_reporter(reporters$multi, lapply(test_paths, test_one_file, expect_equal(obj2.txt1.select.1, obj2.txt1.select.2) obj2.outfile.txt2.select.2 <- tempfile() env = env, desc = desc, shuffle = shuffle, error_call = error_call)) glmm.score(obj2, infile = txtfile2, outfile = obj2.outfile.txt2.select.2, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", 52: test_files_serial(test_dir = test_dir, test_package = test_package, "Allele2")) obj2.txt2.select.2 <- read.table(obj2.outfile.txt2.select.2, test_paths = test_paths, load_helpers = load_helpers, reporter = reporter, header = TRUE, as.is = TRUE) env = env, stop_on_failure = stop_on_failure, stop_on_warning = stop_on_warning, expect_equal(obj2.txt2.select.1, obj2.txt2.select.2) desc = desc, load_package = load_package, shuffle = shuffle, idx <- sample(nrow(kins)) error_call = error_call) kins <- kins[idx, idx] obj1 <- glmmkin(disease ~ age + sex, data = pheno, kins = kins, 53: id = "id", family = binomial(link = "logit"), method = "REML", method.optim = "AI")test_files(test_dir = path, test_paths = test_paths, test_package = package, select <- match(1:400, unique(obj1$id_include)) reporter = reporter, load_helpers = load_helpers, env = env, stop_on_failure = stop_on_failure, stop_on_warning = stop_on_warning, select[is.na(select)] <- 0 obj1.outfile.bed.noselect.3 <- tempfile() load_package = load_package, parallel = parallel, shuffle = shuffle) glmm.score(obj1, infile = plinkfiles, outfile = obj1.outfile.bed.noselect.3) obj1.bed.noselect.3 <- read.table(obj1.outfile.bed.noselect.3, header = TRUE, as.is = TRUE)54: test_dir("testthat", package = package, reporter = reporter, expect_equal(obj1.bed.noselect.1, obj1.bed.noselect.3) obj1.outfile.bed.select.3 <- tempfile() ..., load_package = "installed") glmm.score(obj1, infile = plinkfiles, select = select, outfile = obj1.outfile.bed.select.3) obj1.bed.select.3 <- read.table(obj1.outfile.bed.select.3, 55: header = TRUE, as.is = TRUE) expect_equal(obj1.bed.select.1, obj1.bed.select.3)test_check("GMMAT") obj1.outfile.bgen.noselect.3 <- tempfile() glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, An irrecoverable exception occurred. R is aborting now ... outfile = obj1.outfile.bgen.noselect.3) obj1.bgen.noselect.3 <- read.table(obj1.outfile.bgen.noselect.3, header = TRUE, as.is = TRUE) expect_equal(obj1.bgen.noselect.1, obj1.bgen.noselect.3) obj1.outfile.bgen.select.3 <- tempfile() glmm.score(obj1, infile = bgenfile, BGEN.samplefile = samplefile, select = select, outfile = obj1.outfile.bgen.select.3) obj1.bgen.select.3 <- read.table(obj1.outfile.bgen.select.3, header = TRUE, as.is = TRUE) expect_equal(obj1.bgen.select.1, obj1.bgen.select.3) if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", quietly = TRUE)) { obj1.outfile.gds.noselect.3 <- tempfile() glmm.score(obj1, infile = gdsfile, outfile = obj1.outfile.gds.noselect.3) obj1.gds.noselect.3 <- read.table(obj1.outfile.gds.noselect.3, header = TRUE, as.is = TRUE) expect_equal(obj1.gds.noselect.1, obj1.gds.noselect.3) obj1.outfile.gds.select.3 <- tempfile() glmm.score(obj1, infile = gdsfile, select = select, outfile = obj1.outfile.gds.select.3) obj1.gds.select.3 <- read.table(obj1.outfile.gds.select.3, header = TRUE, as.is = TRUE) expect_equal(obj1.gds.select.1, obj1.gds.select.3) } obj1.outfile.txt.select.3 <- tempfile() glmm.score(obj1, infile = txtfile, outfile = obj1.outfile.txt.select.3, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", "Allele2")) obj1.txt.select.3 <- read.table(obj1.outfile.txt.select.3, header = TRUE, as.is = TRUE) expect_equal(obj1.txt.select.1, obj1.txt.select.3) obj1.outfile.txt1.select.3 <- tempfile() glmm.score(obj1, infile = txtfile1, outfile = obj1.outfile.txt1.select.3, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", "Allele2")) obj1.txt1.select.3 <- read.table(obj1.outfile.txt1.select.3, header = TRUE, as.is = TRUE) expect_equal(obj1.txt1.select.1, obj1.txt1.select.3) obj1.outfile.txt2.select.3 <- tempfile() glmm.score(obj1, infile = txtfile2, outfile = obj1.outfile.txt2.select.3, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", "Allele2")) obj1.txt2.select.3 <- read.table(obj1.outfile.txt2.select.3, header = TRUE, as.is = TRUE) expect_equal(obj1.txt2.select.1, obj1.txt2.select.3) obj2 <- glmmkin(disease ~ age + sex, data = pheno, kins = NULL, id = "id", family = binomial(link = "logit"), method = "REML", method.optim = "AI") select <- match(1:400, unique(obj2$id_include)) select[is.na(select)] <- 0 obj2.outfile.bed.noselect.3 <- tempfile() glmm.score(obj2, infile = plinkfiles, outfile = obj2.outfile.bed.noselect.3) obj2.bed.noselect.3 <- read.table(obj2.outfile.bed.noselect.3, header = TRUE, as.is = TRUE) expect_equal(obj2.bed.noselect.1, obj2.bed.noselect.3) obj2.outfile.bed.select.3 <- tempfile() glmm.score(obj2, infile = plinkfiles, select = select, outfile = obj2.outfile.bed.select.3) obj2.bed.select.3 <- read.table(obj2.outfile.bed.select.3, header = TRUE, as.is = TRUE) expect_equal(obj2.bed.select.1, obj2.bed.select.3) obj2.outfile.bgen.noselect.3 <- tempfile() glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, outfile = obj2.outfile.bgen.noselect.3) obj2.bgen.noselect.3 <- read.table(obj2.outfile.bgen.noselect.3, header = TRUE, as.is = TRUE) expect_equal(obj2.bgen.noselect.1, obj2.bgen.noselect.3) obj2.outfile.bgen.select.3 <- tempfile() glmm.score(obj2, infile = bgenfile, BGEN.samplefile = samplefile, select = select, outfile = obj2.outfile.bgen.select.3) obj2.bgen.select.3 <- read.table(obj2.outfile.bgen.select.3, header = TRUE, as.is = TRUE) expect_equal(obj2.bgen.select.1, obj2.bgen.select.3) if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", quietly = TRUE)) { obj2.outfile.gds.noselect.3 <- tempfile() glmm.score(obj2, infile = gdsfile, outfile = obj2.outfile.gds.noselect.3) obj2.gds.noselect.3 <- read.table(obj2.outfile.gds.noselect.3, header = TRUE, as.is = TRUE) expect_equal(obj2.gds.noselect.1, obj2.gds.noselect.3) obj2.outfile.gds.select.3 <- tempfile() glmm.score(obj2, infile = gdsfile, select = select, outfile = obj2.outfile.gds.select.3) obj2.gds.select.3 <- read.table(obj2.outfile.gds.select.3, header = TRUE, as.is = TRUE) expect_equal(obj2.gds.select.1, obj2.gds.select.3) } obj2.outfile.txt.select.3 <- tempfile() glmm.score(obj2, infile = txtfile, outfile = obj2.outfile.txt.select.3, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", "Allele2")) obj2.txt.select.3 <- read.table(obj2.outfile.txt.select.3, header = TRUE, as.is = TRUE) expect_equal(obj2.txt.select.1, obj2.txt.select.3) obj2.outfile.txt1.select.3 <- tempfile() glmm.score(obj2, infile = txtfile1, outfile = obj2.outfile.txt1.select.3, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", "Allele2")) obj2.txt1.select.3 <- read.table(obj2.outfile.txt1.select.3, header = TRUE, as.is = TRUE) expect_equal(obj2.txt1.select.1, obj2.txt1.select.3) obj2.outfile.txt2.select.3 <- tempfile() glmm.score(obj2, infile = txtfile2, outfile = obj2.outfile.txt2.select.3, infile.nrow.skip = 5, infile.ncol.skip = 3, infile.ncol.print = 1:3, select = select, infile.header.print = c("SNP", "Allele1", "Allele2")) obj2.txt2.select.3 <- read.table(obj2.outfile.txt2.select.3, header = TRUE, as.is = TRUE) expect_equal(obj2.txt2.select.1, obj2.txt2.select.3) unlink(c(obj2.outfile.bed.noselect.1, obj2.outfile.bed.select.1, obj2.outfile.bgen.noselect.1, obj2.outfile.bgen.select.1, obj2.outfile.txt.select.1, obj2.outfile.txt1.select.1, obj2.outfile.txt2.select.1)) unlink(c(obj1.outfile.bed.noselect.2, obj1.outfile.bed.select.2, obj1.outfile.bgen.noselect.2, obj1.outfile.bgen.select.2, obj1.outfile.txt.select.2, obj1.outfile.txt1.select.2, obj1.outfile.txt2.select.2)) unlink(c(obj2.outfile.bed.noselect.2, obj2.outfile.bed.select.2, obj2.outfile.bgen.noselect.2, obj2.outfile.bgen.select.2, obj2.outfile.txt.select.2, obj2.outfile.txt1.select.2, obj2.outfile.txt2.select.2)) unlink(c(obj1.outfile.bed.noselect.3, obj1.outfile.bed.select.3, obj1.outfile.bgen.noselect.3, obj1.outfile.bgen.select.3, obj1.outfile.txt.select.3, obj1.outfile.txt1.select.3, obj1.outfile.txt2.select.3)) unlink(c(obj2.outfile.bed.noselect.3, obj2.outfile.bed.select.3, obj2.outfile.bgen.noselect.3, obj2.outfile.bgen.select.3, obj2.outfile.txt.select.3, obj2.outfile.txt1.select.3, obj2.outfile.txt2.select.3)) if (requireNamespace("SeqArray", quietly = TRUE) && requireNamespace("SeqVarTools", quietly = TRUE)) unlink(c(obj2.outfile.gds.noselect.1, obj2.outfile.gds.select.1, obj1.outfile.gds.noselect.2, obj1.outfile.gds.select.2, obj2.outfile.gds.noselect.2, obj2.outfile.gds.select.2, obj1.outfile.gds.noselect.3, obj1.outfile.gds.select.3, obj2.outfile.gds.noselect.3, obj2.outfile.gds.select.3))}) 33: eval(code, test_env) 34: eval(code, test_env) 35: withCallingHandlers({ eval(code, test_env) new_expectations <- the$test_expectations > starting_expectations if (snapshot_skipped) { skip("On CRAN") } else if (!new_expectations && skip_on_empty) { skip_empty() }}, expectation = handle_expectation, packageNotFoundError = function(e) { if (on_cran()) { skip(paste0("{", e$package, "} is not installed.")) }}, snapshot_on_cran = function(cnd) { snapshot_skipped <<- TRUE invokeRestart("muffle_cran_snapshot")}, skip = handle_skip, warning = handle_warning, message = handle_message, error = handle_error, interrupt = handle_interrupt) 36: doTryCatch(return(expr), name, parentenv, handler) 37: tryCatchOne(expr, names, parentenv, handlers[[1L]]) 38: tryCatchList(expr, classes, parentenv, handlers) 39: tryCatch(withCallingHandlers({ eval(code, test_env) new_expectations <- the$test_expectations > starting_expectations if (snapshot_skipped) { skip("On CRAN") } else if (!new_expectations && skip_on_empty) { skip_empty() }}, expectation = handle_expectation, packageNotFoundError = function(e) { if (on_cran()) { skip(paste0("{", e$package, "} is not installed.")) }}, snapshot_on_cran = function(cnd) { snapshot_skipped <<- TRUE invokeRestart("muffle_cran_snapshot")}, skip = handle_skip, warning = handle_warning, message = handle_message, error = handle_error, interrupt = handle_interrupt), error = handle_fatal) 40: doWithOneRestart(return(expr), restart) 41: withOneRestart(expr, restarts[[1L]]) 42: withRestarts(tryCatch(withCallingHandlers({ eval(code, test_env) new_expectations <- the$test_expectations > starting_expectations if (snapshot_skipped) { skip("On CRAN") } else if (!new_expectations && skip_on_empty) { skip_empty() }}, expectation = handle_expectation, packageNotFoundError = function(e) { if (on_cran()) { skip(paste0("{", e$package, "} is not installed.")) }}, snapshot_on_cran = function(cnd) { snapshot_skipped <<- TRUE invokeRestart("muffle_cran_snapshot")}, skip = handle_skip, warning = handle_warning, message = handle_message, error = handle_error, interrupt = handle_interrupt), error = handle_fatal), end_test = function() { }) 43: test_code(code = exprs, env = env, reporter = get_reporter() %||% StopReporter$new()) 44: source_file(path, env = env(env), desc = desc, shuffle = shuffle, error_call = error_call) 45: FUN(X[[i]], ...) 46: lapply(test_paths, test_one_file, env = env, desc = desc, shuffle = shuffle, error_call = error_call) 47: doTryCatch(return(expr), name, parentenv, handler) 48: tryCatchOne(expr, names, parentenv, handlers[[1L]]) 49: tryCatchList(expr, classes, parentenv, handlers) 50: tryCatch(code, testthat_abort_reporter = function(cnd) { cat(conditionMessage(cnd), "\n") NULL}) 51: with_reporter(reporters$multi, lapply(test_paths, test_one_file, env = env, desc = desc, shuffle = shuffle, error_call = error_call)) 52: test_files_serial(test_dir = test_dir, test_package = test_package, test_paths = test_paths, load_helpers = load_helpers, reporter = reporter, env = env, stop_on_failure = stop_on_failure, stop_on_warning = stop_on_warning, desc = desc, load_package = load_package, shuffle = shuffle, error_call = error_call) 53: test_files(test_dir = path, test_paths = test_paths, test_package = package, reporter = reporter, load_helpers = load_helpers, env = env, stop_on_failure = stop_on_failure, stop_on_warning = stop_on_warning, load_package = load_package, parallel = parallel, shuffle = shuffle) 54: test_dir("testthat", package = package, reporter = reporter, ..., load_package = "installed") 55: test_check("GMMAT") An irrecoverable exception occurred. R is aborting now ... Saving _problems/test_glmm.score-37.R The following SNPs have been removed due to inconsistent alleles across studies: [1] "L10" "L12" "L15" [ FAIL 1 | WARN 2 | SKIP 30 | PASS 3 ] ══ Skipped tests (30) ══════════════════════════════════════════════════════════ • On CRAN (28): 'test_SMMAT.R:56:2', 'test_SMMAT.R:103:2', 'test_SMMAT.R:149:2', 'test_SMMAT.R:196:2', 'test_SMMAT.R:236:2', 'test_SMMAT.R:276:2', 'test_SMMAT.meta.R:45:2', 'test_SMMAT.meta.R:77:2', 'test_SMMAT.meta.R:108:2', 'test_SMMAT.meta.R:140:2', 'test_SMMAT.meta.R:165:2', 'test_glmm.score.R:317:2', 'test_glmm.score.R:616:2', 'test_glmm.score.R:914:2', 'test_glmm.score.R:1213:2', 'test_glmm.score.R:1505:2', 'test_glmm.score.R:1797:2', 'test_glmm.wald.R:2:2', 'test_glmm.wald.R:805:2', 'test_glmm.wald.R:1609:2', 'test_glmm.wald.R:1761:2', 'test_glmmkin.R:2:2', 'test_glmmkin.R:82:2', 'test_glmmkin.R:163:2', 'test_glmmkin.R:245:2', 'test_glmmkin.R:328:2', 'test_glmmkin.R:362:2', 'test_glmmkin.R:396:2' • {SeqArray} is not installed (2): 'test_SMMAT.R:2:9', 'test_SMMAT.meta.R:2:2' ══ Failed tests ════════════════════════════════════════════════════════════════ ── Error ('test_glmm.score.R:37:2'): cross-sectional id le 400 binomial ──────── Error in `file(outfile, "w")`: cannot open the connection Backtrace: ▆ 1. └─GMMAT::glmm.score(...) at test_glmm.score.R:37:9 2. └─base::file(outfile, "w") [ FAIL 1 | WARN 2 | SKIP 30 | PASS 3 ] Error: ! Test failures. Execution halted Flavor: r-oldrel-macos-arm64

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